Psychogenic nonepileptic seizures mimicking gelastic seizures: A description of two cases

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Psychogenic nonepileptic seizures (PNES) are sudden, involuntary seizure-like attacks that, unlike epileptic seizures, are not related to electrographic ictal discharges and are psychological in nature. Psychogenic nonepileptic seizures presenting symptoms mimic a wide array of nervous system dysfunctions, as they involve changes in behavior, motor activity, sensation, cognitive, and autonomic functions. Spontaneous paroxysms of laughing resembling gelastic seizure have only exceptionally been reported as main symptom of PNES. Here,we describe the cases of two patientswith a prolonged history of laughter attacks mistaken for epilepsy and unresponsive to AED treatment. BrainMRI and interictal EEG were unremarkable. Video-EEGmonitoring allowed us to document the spontaneous and suggestion-induced habitual episodes that were then diagnosed as PNES.

Original languageEnglish
Pages (from-to)67-69
Number of pages3
JournalEpilepsy and Behavior Case Reports
Publication statusPublished - Jun 1 2015


  • Gelastic seizures
  • Psychogenic nonepileptic seizure
  • Video-EEG monitoring

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Neurology
  • Clinical Neurology


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