Psychometrics evaluation of Charcot-Marie-Tooth Neuropathy Score (CMTNSv2) second version, using Rasch analysis

Reza Sadjadi, Mary M. Reilly, Michael E. Shy, Davide Pareyson, Matilde Laura, Sinead Murphy, Shawna M E Feely, Tiffany Grider, Chelsea Bacon, Giuseppe Piscosquito, Daniela Calabrese, Ted M. Burns

Research output: Contribution to journalArticlepeer-review

Abstract

Charcot-Marie-Tooth Neuropathy Score second version (CMTNSv2) is a validated clinical outcome measure developed for use in clinical trials to monitor disease impairment and progression in affected CMT patients. Currently, all items of CMTNSv2 have identical contribution to the total score. We used Rasch analysis to further explore psychometric properties of CMTNSv2, and in particular, category response functioning, and their weight on the overall disease progression. Weighted category responses represent a more accurate estimate of actual values measuring disease severity and therefore could potentially be used in improving the current version.

Original languageEnglish
Pages (from-to)192-196
Number of pages5
JournalJournal of the Peripheral Nervous System
Volume19
Issue number3
DOIs
Publication statusPublished - Sep 1 2014

Keywords

  • Charcot-Marie-Tooth
  • Charcot-Marie-Tooth Neuropathy Score (CMTNS2) second version
  • outcome measures
  • psychometrics
  • Rasch analysis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Psychometrics evaluation of Charcot-Marie-Tooth Neuropathy Score (CMTNSv2) second version, using Rasch analysis'. Together they form a unique fingerprint.

Cite this