Psychopathological features of obsessive-compulsive disorder in an Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene

Massimo Pasquini, Giovanni Fabbrini, Isabella Berardelli, Vincenzo Bonifati, Massimo Biondi, Alfredo Berardelli

Research output: Contribution to journalArticle

Abstract

We report the psychopathological features in a large Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene. Of the 23 living family members, 14 were evaluated using the Structured Clinical Interview for DSM-IV, the Yale-Brown Obsessive-Compulsive Scale, the Clinical Global Impression and the Global Assessment of Functioning scale. Ten patients were found to have obsessive-compulsive disorder in which tic-like compulsions predominated. The distinctive feature of this family is the high frequency of obsessive-compulsive disorder with various clinical phenotypes.

Original languageEnglish
Pages (from-to)109-111
Number of pages3
JournalPsychiatry Research
Volume161
Issue number1
DOIs
Publication statusPublished - Oct 30 2008

Fingerprint

Tourette Syndrome
Obsessive-Compulsive Disorder
Genes
Tics
Diagnostic and Statistical Manual of Mental Disorders
Interviews
Phenotype

Keywords

  • Clinical features
  • Gilles de la Tourette
  • Italian family
  • Obsessive-compulsive disorder
  • SLITRK1 gene

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

Cite this

Psychopathological features of obsessive-compulsive disorder in an Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene. / Pasquini, Massimo; Fabbrini, Giovanni; Berardelli, Isabella; Bonifati, Vincenzo; Biondi, Massimo; Berardelli, Alfredo.

In: Psychiatry Research, Vol. 161, No. 1, 30.10.2008, p. 109-111.

Research output: Contribution to journalArticle

@article{49b819f115de47b89ebb5d8c3ed9b0cb,
title = "Psychopathological features of obsessive-compulsive disorder in an Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene",
abstract = "We report the psychopathological features in a large Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene. Of the 23 living family members, 14 were evaluated using the Structured Clinical Interview for DSM-IV, the Yale-Brown Obsessive-Compulsive Scale, the Clinical Global Impression and the Global Assessment of Functioning scale. Ten patients were found to have obsessive-compulsive disorder in which tic-like compulsions predominated. The distinctive feature of this family is the high frequency of obsessive-compulsive disorder with various clinical phenotypes.",
keywords = "Clinical features, Gilles de la Tourette, Italian family, Obsessive-compulsive disorder, SLITRK1 gene",
author = "Massimo Pasquini and Giovanni Fabbrini and Isabella Berardelli and Vincenzo Bonifati and Massimo Biondi and Alfredo Berardelli",
year = "2008",
month = "10",
day = "30",
doi = "10.1016/j.psychres.2008.02.012",
language = "English",
volume = "161",
pages = "109--111",
journal = "Psychiatry Research",
issn = "0165-1781",
publisher = "Elsevier Ireland Ltd",
number = "1",

}

TY - JOUR

T1 - Psychopathological features of obsessive-compulsive disorder in an Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene

AU - Pasquini, Massimo

AU - Fabbrini, Giovanni

AU - Berardelli, Isabella

AU - Bonifati, Vincenzo

AU - Biondi, Massimo

AU - Berardelli, Alfredo

PY - 2008/10/30

Y1 - 2008/10/30

N2 - We report the psychopathological features in a large Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene. Of the 23 living family members, 14 were evaluated using the Structured Clinical Interview for DSM-IV, the Yale-Brown Obsessive-Compulsive Scale, the Clinical Global Impression and the Global Assessment of Functioning scale. Ten patients were found to have obsessive-compulsive disorder in which tic-like compulsions predominated. The distinctive feature of this family is the high frequency of obsessive-compulsive disorder with various clinical phenotypes.

AB - We report the psychopathological features in a large Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene. Of the 23 living family members, 14 were evaluated using the Structured Clinical Interview for DSM-IV, the Yale-Brown Obsessive-Compulsive Scale, the Clinical Global Impression and the Global Assessment of Functioning scale. Ten patients were found to have obsessive-compulsive disorder in which tic-like compulsions predominated. The distinctive feature of this family is the high frequency of obsessive-compulsive disorder with various clinical phenotypes.

KW - Clinical features

KW - Gilles de la Tourette

KW - Italian family

KW - Obsessive-compulsive disorder

KW - SLITRK1 gene

UR - http://www.scopus.com/inward/record.url?scp=52149083492&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=52149083492&partnerID=8YFLogxK

U2 - 10.1016/j.psychres.2008.02.012

DO - 10.1016/j.psychres.2008.02.012

M3 - Article

C2 - 18722020

AN - SCOPUS:52149083492

VL - 161

SP - 109

EP - 111

JO - Psychiatry Research

JF - Psychiatry Research

SN - 0165-1781

IS - 1

ER -