Psychopathological features of obsessive-compulsive disorder in an Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene

Massimo Pasquini, Giovanni Fabbrini, Isabella Berardelli, Vincenzo Bonifati, Massimo Biondi, Alfredo Berardelli

Research output: Contribution to journalArticlepeer-review

Abstract

We report the psychopathological features in a large Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene. Of the 23 living family members, 14 were evaluated using the Structured Clinical Interview for DSM-IV, the Yale-Brown Obsessive-Compulsive Scale, the Clinical Global Impression and the Global Assessment of Functioning scale. Ten patients were found to have obsessive-compulsive disorder in which tic-like compulsions predominated. The distinctive feature of this family is the high frequency of obsessive-compulsive disorder with various clinical phenotypes.

Original languageEnglish
Pages (from-to)109-111
Number of pages3
JournalPsychiatry Research
Volume161
Issue number1
DOIs
Publication statusPublished - Oct 30 2008

Keywords

  • Clinical features
  • Gilles de la Tourette
  • Italian family
  • Obsessive-compulsive disorder
  • SLITRK1 gene

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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