20 out-patients, affected by Schizophrenia or Personality Disorders according to DSM-IV, treated with risperidone (RSP) at a mean dosage of 4.46 mg ± 1.35 SD for 12 months, were included in the study. 5 patients also benefitted from psychotherapy, 5 participated in rehabilitation and re- socialisation groups while 10 received psychoeducational/supportive interventions. BPRS and PANSS total score (mean values) showed a significant decrease during the study. No correlation between RSP dosage and RSP or its metabolite, 9 hydroxy-risperidone (9OH-RSP) plasma levels resulted. No linear relationship between RSP plasma levels or active moiety and clinical improvement was observed. RSP therapy facilitated the psychotherapeutic compliance, re-socialisation processes and participation in groups, improving patients quality of life and relational modalities.
|Number of pages||5|
|Journal||New Trends in Experimental and Clinical Psychiatry|
|Publication status||Published - 1999|
- Psychotherapy-rehabilitative approach
ASJC Scopus subject areas
- Psychiatry and Mental health