Psychosis in a cocaine-dependent patient with ADHD during treatment with methylphenidate

Héloïse Delavenne, Frederico Duarte Garcia, Jér Ôme Lacoste, Samuele Cortese, Aimé Charles-Nicolas, Nicolas Ballon

Research output: Contribution to journalArticlepeer-review


Objective: The objective was to report a case of experienced psychosis during the treatment with methylphenidate (MPH) in a cocaine-dependent adult treated for attention-deficit/hyperactivity disorder (ADHD) with comorbid cocaine dependence. Conclusion: ADHD is a frequent comorbidity in substance use disorder (SUD) patients. MPH may be effective in treating ADHD symptoms in SUD patients, thus preventing possible adverse outcomes. Cocaine-induced psychosis may be a risk factor for development of psychosis in the presence of a concurrent treatment with MPH.

Original languageEnglish
JournalGeneral Hospital Psychiatry
Issue number4
Publication statusPublished - Jul 2013


  • ADHD
  • Adverse effect
  • Cocaine
  • Dopamine
  • Methylphenidate
  • Psychosis-induced
  • Substance use disorder

ASJC Scopus subject areas

  • Psychiatry and Mental health


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