Psychosocial difficulties in patients with Parkinson's disease

Silvia Schiavolin, Alberto Raggi, Rui Quintas, Milda Cerniauskaite, Ambra M. Giovannetti, Venusia Covelli, Luigi Romito, Antonio E. Elia, Francesco Carella, Paola Soliveri, Matilde Leonardi

Research output: Contribution to journalArticlepeer-review


The aim of this study was to report the most frequent psychosocial difficulties (PSDs) in patients with Parkinson disease (PD), to explore the relationship between PSDs, disability and quality of life (QoL), and to address the predictors of PSDs. Patients with PD were interviewed using a protocol composed of a questionnaire investigating PSDs (PARADISE 24), QoL, disability, comorbidity, and social support questionnaires, scales on resilience, personality traits, and empathy in physician. Most frequent PSDs were reported. Spearman's correlation was used to address the relationship between PARADISE 24 and QoL and disability measures. Multiple linear regression was performed to investigate predictors of PARADISE 24. Eighty patients were enrolled: 40% women, mean age 61.2 years. The most frequent PSDs were related to cognitive and motor slowness, tiredness, sleeping, facing all things to do, depressive mood, and anxiety. PARADISE 24 were correlated with disability (ρ=0.831) and QoL (ρ=-0.685). Lower QoL, higher disability, early age at onset, and shorter disease duration were significant predictors of PSDs (adjusted R 2 =0.762). PARADISE 24 is an easy to use questionnaire that could contribute toward describing the impact of PD on patients' life more extensively, thus helping to define more tailored interventions.

Original languageEnglish
Pages (from-to)112-118
Number of pages7
JournalInternational Journal of Rehabilitation Research
Issue number2
Publication statusPublished - Jan 1 2017


  • age of onset
  • disability evaluation
  • disease duration
  • horizontal epidemiology
  • Parkinson's disease
  • psychosocial difficulties
  • quality of life

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation


Dive into the research topics of 'Psychosocial difficulties in patients with Parkinson's disease'. Together they form a unique fingerprint.

Cite this