Psychotropic drug utilization in Europe: Results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project

J. Alonso, M. C. Angermeyer, S. Bernert, R. Bruffaerts, T. S. Brugha, H. Bryson, G. De Girolamo, R. De Graaf, K. Demyttenaere, I. Gasquet, J. M. Haro, S. J. Katz, R. C. Kessler, V. Kovess, J. P. Lépine, J. Ormel, G. Polidori, L. J. Russo, G. Vilagut, J. AlmansaS. Arbabzadeh-Bouchez, J. Autonell, M. Bernal, M. A. Buist-Bouwman, M. Codony, A. Domingo-Salvany, M. Ferrer, S. S. Joo, M. Martínez-Alonso, H. Matschinger, F. Mazzi, Z. Morgan, P. Morosini, C. Palacín, B. Romera, N. Taub, W. A M Vollebergh

Research output: Contribution to journalArticle

215 Citations (Scopus)

Abstract

Objective: To assess psychotropic drug utilization in the general population of six European countries, and the pattern of use in individuals with different DSM-IV diagnoses of 12-month mental disorders. Method: Data were derived from the European Study of the Epidemiology of Mental Disorders (ESEMeD/MHEDEA 2000), a cross-sectional psychiatric epidemiological study in a representative sample of 21 425 adults aged 18 or older from six European countries (e.g. Belgium, France, Germany, Italy, the Netherlands and Spain). Individuals were asked about any psychotropic drug use in the past 12 months, even if they used the drug(s) just once. A colour booklet containing high-quality pictures of psychotropic drugs commonly used to treat mental disorders was provided to help respondents recall drug use. Results: Psychotropic drug utilization is generally low in individuals with any 12-month mental disorder (32.6%). The extent of psychotropic drug utilization varied according to the specific DSM-IV diagnosis. Among individuals with a 12-month diagnosis of pure major depression, only 21.2% had received any antidepressants within the same period; the exclusive use of antidepressants was even lower (4.6%), while more individuals took only anxiolytics (18.4%). Conclusion: These data question the appropriateness of current pharmacological treatments, particularly for major depression, in which under-treatment is coupled with the high use of non-specific medications, such as anxiolytics.

Original languageEnglish
Pages (from-to)55-64
Number of pages10
JournalActa Psychiatrica Scandinavica, Supplement
Volume109
Issue number420
Publication statusPublished - Jun 2004

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Drug Utilization
Psychotropic Drugs
Mental Disorders
Epidemiology
Anti-Anxiety Agents
Diagnostic and Statistical Manual of Mental Disorders
Antidepressive Agents
Drug Recalls
Depression
Pamphlets
Belgium
Netherlands
Spain
Italy
France
Germany
Psychiatry
Epidemiologic Studies
Color
Pharmacology

Keywords

  • Antidepressant
  • Anxiolytic
  • Mental disorders
  • Pharmacoepidemiology
  • Psychotropic drugs

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience(all)

Cite this

Alonso, J., Angermeyer, M. C., Bernert, S., Bruffaerts, R., Brugha, T. S., Bryson, H., ... Vollebergh, W. A. M. (2004). Psychotropic drug utilization in Europe: Results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatrica Scandinavica, Supplement, 109(420), 55-64.

Psychotropic drug utilization in Europe : Results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. / Alonso, J.; Angermeyer, M. C.; Bernert, S.; Bruffaerts, R.; Brugha, T. S.; Bryson, H.; De Girolamo, G.; De Graaf, R.; Demyttenaere, K.; Gasquet, I.; Haro, J. M.; Katz, S. J.; Kessler, R. C.; Kovess, V.; Lépine, J. P.; Ormel, J.; Polidori, G.; Russo, L. J.; Vilagut, G.; Almansa, J.; Arbabzadeh-Bouchez, S.; Autonell, J.; Bernal, M.; Buist-Bouwman, M. A.; Codony, M.; Domingo-Salvany, A.; Ferrer, M.; Joo, S. S.; Martínez-Alonso, M.; Matschinger, H.; Mazzi, F.; Morgan, Z.; Morosini, P.; Palacín, C.; Romera, B.; Taub, N.; Vollebergh, W. A M.

In: Acta Psychiatrica Scandinavica, Supplement, Vol. 109, No. 420, 06.2004, p. 55-64.

Research output: Contribution to journalArticle

Alonso, J, Angermeyer, MC, Bernert, S, Bruffaerts, R, Brugha, TS, Bryson, H, De Girolamo, G, De Graaf, R, Demyttenaere, K, Gasquet, I, Haro, JM, Katz, SJ, Kessler, RC, Kovess, V, Lépine, JP, Ormel, J, Polidori, G, Russo, LJ, Vilagut, G, Almansa, J, Arbabzadeh-Bouchez, S, Autonell, J, Bernal, M, Buist-Bouwman, MA, Codony, M, Domingo-Salvany, A, Ferrer, M, Joo, SS, Martínez-Alonso, M, Matschinger, H, Mazzi, F, Morgan, Z, Morosini, P, Palacín, C, Romera, B, Taub, N & Vollebergh, WAM 2004, 'Psychotropic drug utilization in Europe: Results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project', Acta Psychiatrica Scandinavica, Supplement, vol. 109, no. 420, pp. 55-64.
Alonso, J. ; Angermeyer, M. C. ; Bernert, S. ; Bruffaerts, R. ; Brugha, T. S. ; Bryson, H. ; De Girolamo, G. ; De Graaf, R. ; Demyttenaere, K. ; Gasquet, I. ; Haro, J. M. ; Katz, S. J. ; Kessler, R. C. ; Kovess, V. ; Lépine, J. P. ; Ormel, J. ; Polidori, G. ; Russo, L. J. ; Vilagut, G. ; Almansa, J. ; Arbabzadeh-Bouchez, S. ; Autonell, J. ; Bernal, M. ; Buist-Bouwman, M. A. ; Codony, M. ; Domingo-Salvany, A. ; Ferrer, M. ; Joo, S. S. ; Martínez-Alonso, M. ; Matschinger, H. ; Mazzi, F. ; Morgan, Z. ; Morosini, P. ; Palacín, C. ; Romera, B. ; Taub, N. ; Vollebergh, W. A M. / Psychotropic drug utilization in Europe : Results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. In: Acta Psychiatrica Scandinavica, Supplement. 2004 ; Vol. 109, No. 420. pp. 55-64.
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abstract = "Objective: To assess psychotropic drug utilization in the general population of six European countries, and the pattern of use in individuals with different DSM-IV diagnoses of 12-month mental disorders. Method: Data were derived from the European Study of the Epidemiology of Mental Disorders (ESEMeD/MHEDEA 2000), a cross-sectional psychiatric epidemiological study in a representative sample of 21 425 adults aged 18 or older from six European countries (e.g. Belgium, France, Germany, Italy, the Netherlands and Spain). Individuals were asked about any psychotropic drug use in the past 12 months, even if they used the drug(s) just once. A colour booklet containing high-quality pictures of psychotropic drugs commonly used to treat mental disorders was provided to help respondents recall drug use. Results: Psychotropic drug utilization is generally low in individuals with any 12-month mental disorder (32.6{\%}). The extent of psychotropic drug utilization varied according to the specific DSM-IV diagnosis. Among individuals with a 12-month diagnosis of pure major depression, only 21.2{\%} had received any antidepressants within the same period; the exclusive use of antidepressants was even lower (4.6{\%}), while more individuals took only anxiolytics (18.4{\%}). Conclusion: These data question the appropriateness of current pharmacological treatments, particularly for major depression, in which under-treatment is coupled with the high use of non-specific medications, such as anxiolytics.",
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author = "J. Alonso and Angermeyer, {M. C.} and S. Bernert and R. Bruffaerts and Brugha, {T. S.} and H. Bryson and {De Girolamo}, G. and {De Graaf}, R. and K. Demyttenaere and I. Gasquet and Haro, {J. M.} and Katz, {S. J.} and Kessler, {R. C.} and V. Kovess and L{\'e}pine, {J. P.} and J. Ormel and G. Polidori and Russo, {L. J.} and G. Vilagut and J. Almansa and S. Arbabzadeh-Bouchez and J. Autonell and M. Bernal and Buist-Bouwman, {M. A.} and M. Codony and A. Domingo-Salvany and M. Ferrer and Joo, {S. S.} and M. Mart{\'i}nez-Alonso and H. Matschinger and F. Mazzi and Z. Morgan and P. Morosini and C. Palac{\'i}n and B. Romera and N. Taub and Vollebergh, {W. A M}",
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T2 - Results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project

AU - Alonso, J.

AU - Angermeyer, M. C.

AU - Bernert, S.

AU - Bruffaerts, R.

AU - Brugha, T. S.

AU - Bryson, H.

AU - De Girolamo, G.

AU - De Graaf, R.

AU - Demyttenaere, K.

AU - Gasquet, I.

AU - Haro, J. M.

AU - Katz, S. J.

AU - Kessler, R. C.

AU - Kovess, V.

AU - Lépine, J. P.

AU - Ormel, J.

AU - Polidori, G.

AU - Russo, L. J.

AU - Vilagut, G.

AU - Almansa, J.

AU - Arbabzadeh-Bouchez, S.

AU - Autonell, J.

AU - Bernal, M.

AU - Buist-Bouwman, M. A.

AU - Codony, M.

AU - Domingo-Salvany, A.

AU - Ferrer, M.

AU - Joo, S. S.

AU - Martínez-Alonso, M.

AU - Matschinger, H.

AU - Mazzi, F.

AU - Morgan, Z.

AU - Morosini, P.

AU - Palacín, C.

AU - Romera, B.

AU - Taub, N.

AU - Vollebergh, W. A M

PY - 2004/6

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N2 - Objective: To assess psychotropic drug utilization in the general population of six European countries, and the pattern of use in individuals with different DSM-IV diagnoses of 12-month mental disorders. Method: Data were derived from the European Study of the Epidemiology of Mental Disorders (ESEMeD/MHEDEA 2000), a cross-sectional psychiatric epidemiological study in a representative sample of 21 425 adults aged 18 or older from six European countries (e.g. Belgium, France, Germany, Italy, the Netherlands and Spain). Individuals were asked about any psychotropic drug use in the past 12 months, even if they used the drug(s) just once. A colour booklet containing high-quality pictures of psychotropic drugs commonly used to treat mental disorders was provided to help respondents recall drug use. Results: Psychotropic drug utilization is generally low in individuals with any 12-month mental disorder (32.6%). The extent of psychotropic drug utilization varied according to the specific DSM-IV diagnosis. Among individuals with a 12-month diagnosis of pure major depression, only 21.2% had received any antidepressants within the same period; the exclusive use of antidepressants was even lower (4.6%), while more individuals took only anxiolytics (18.4%). Conclusion: These data question the appropriateness of current pharmacological treatments, particularly for major depression, in which under-treatment is coupled with the high use of non-specific medications, such as anxiolytics.

AB - Objective: To assess psychotropic drug utilization in the general population of six European countries, and the pattern of use in individuals with different DSM-IV diagnoses of 12-month mental disorders. Method: Data were derived from the European Study of the Epidemiology of Mental Disorders (ESEMeD/MHEDEA 2000), a cross-sectional psychiatric epidemiological study in a representative sample of 21 425 adults aged 18 or older from six European countries (e.g. Belgium, France, Germany, Italy, the Netherlands and Spain). Individuals were asked about any psychotropic drug use in the past 12 months, even if they used the drug(s) just once. A colour booklet containing high-quality pictures of psychotropic drugs commonly used to treat mental disorders was provided to help respondents recall drug use. Results: Psychotropic drug utilization is generally low in individuals with any 12-month mental disorder (32.6%). The extent of psychotropic drug utilization varied according to the specific DSM-IV diagnosis. Among individuals with a 12-month diagnosis of pure major depression, only 21.2% had received any antidepressants within the same period; the exclusive use of antidepressants was even lower (4.6%), while more individuals took only anxiolytics (18.4%). Conclusion: These data question the appropriateness of current pharmacological treatments, particularly for major depression, in which under-treatment is coupled with the high use of non-specific medications, such as anxiolytics.

KW - Antidepressant

KW - Anxiolytic

KW - Mental disorders

KW - Pharmacoepidemiology

KW - Psychotropic drugs

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