pTNM stage distribution in breast cancer: A population-based survey in northern Italy

S. Rodella, M. Turazza, C. Picoco, F. Stanzial, F. Bonetti, A. M. Molino, L. F. Donati, E. Buongiorno, G. Calabrese, P. Castelli, M. Lestani, F. Marino, R. Mencarelli, G. Pelosi

Research output: Contribution to journalArticle

Abstract

Aims and background: The role of distribution by stage at diagnosis in breast cancer has been considered in many studies, with particular regard to evaluation of prognosis, impact of screening programs and quality of care. Nevertheless, international comparisons of descriptive data can be hampered by lack of homogeneity in staging methods. The TNM is presently the most common staging system used all over the world, although some criticism have been raised recently against its pragmatic value. The present study reports a population-based survey of pathologic TNM distribution in incident cases of female breast cancer in the Verona province, a geographical area of northern Italy covered by cancer registration. Methods: All histologically proven incident cases of breast cancer were identified in the study period 1988-1990 and classified as for tumor size and nodal involvement according to the pathological TNM criteria. The type of surgical treatment was also registered for all cases diagnosed in 1990. Results: one thousand two hundreds and fifty-four invasive and in situ breast cancers were observed and pT1 cases accounted for 44.4%. Nodal involvement was present in 41.5% of invasive cancers. A surgical treatment was performed in 1213 patients (96.7%). Axillary dissection was reported in 1080 cases, 820 of them (76.6%) having 10 or more lymph nodes examined. Radical mastectomy accounted for 74% of the 458 breast cancers diagnosed in 1990 and 31.6% of the eligible cases were conservatively treated. Conclusions: Cancer registries should be encouraged to report data on stage distribution in breast cancer (and in other malignancies). This practice could improve international comparisons and give an essential contribution to studies on survival, screening programs and quality of care.

Original languageEnglish
Pages (from-to)263-268
Number of pages6
JournalTumori
Volume80
Issue number4
Publication statusPublished - 1994

Fingerprint

Italy
Breast Neoplasms
Population
Quality of Health Care
Neoplasms
Radical Mastectomy
Registries
Surveys and Questionnaires
Dissection
Lymph Nodes
Survival
Therapeutics

Keywords

  • breast cancer
  • cancer registries
  • staging

ASJC Scopus subject areas

  • Cancer Research

Cite this

Rodella, S., Turazza, M., Picoco, C., Stanzial, F., Bonetti, F., Molino, A. M., ... Pelosi, G. (1994). pTNM stage distribution in breast cancer: A population-based survey in northern Italy. Tumori, 80(4), 263-268.

pTNM stage distribution in breast cancer : A population-based survey in northern Italy. / Rodella, S.; Turazza, M.; Picoco, C.; Stanzial, F.; Bonetti, F.; Molino, A. M.; Donati, L. F.; Buongiorno, E.; Calabrese, G.; Castelli, P.; Lestani, M.; Marino, F.; Mencarelli, R.; Pelosi, G.

In: Tumori, Vol. 80, No. 4, 1994, p. 263-268.

Research output: Contribution to journalArticle

Rodella, S, Turazza, M, Picoco, C, Stanzial, F, Bonetti, F, Molino, AM, Donati, LF, Buongiorno, E, Calabrese, G, Castelli, P, Lestani, M, Marino, F, Mencarelli, R & Pelosi, G 1994, 'pTNM stage distribution in breast cancer: A population-based survey in northern Italy', Tumori, vol. 80, no. 4, pp. 263-268.
Rodella S, Turazza M, Picoco C, Stanzial F, Bonetti F, Molino AM et al. pTNM stage distribution in breast cancer: A population-based survey in northern Italy. Tumori. 1994;80(4):263-268.
Rodella, S. ; Turazza, M. ; Picoco, C. ; Stanzial, F. ; Bonetti, F. ; Molino, A. M. ; Donati, L. F. ; Buongiorno, E. ; Calabrese, G. ; Castelli, P. ; Lestani, M. ; Marino, F. ; Mencarelli, R. ; Pelosi, G. / pTNM stage distribution in breast cancer : A population-based survey in northern Italy. In: Tumori. 1994 ; Vol. 80, No. 4. pp. 263-268.
@article{2a87d9ddd75f4eb6a03e781a6b0fb5f4,
title = "pTNM stage distribution in breast cancer: A population-based survey in northern Italy",
abstract = "Aims and background: The role of distribution by stage at diagnosis in breast cancer has been considered in many studies, with particular regard to evaluation of prognosis, impact of screening programs and quality of care. Nevertheless, international comparisons of descriptive data can be hampered by lack of homogeneity in staging methods. The TNM is presently the most common staging system used all over the world, although some criticism have been raised recently against its pragmatic value. The present study reports a population-based survey of pathologic TNM distribution in incident cases of female breast cancer in the Verona province, a geographical area of northern Italy covered by cancer registration. Methods: All histologically proven incident cases of breast cancer were identified in the study period 1988-1990 and classified as for tumor size and nodal involvement according to the pathological TNM criteria. The type of surgical treatment was also registered for all cases diagnosed in 1990. Results: one thousand two hundreds and fifty-four invasive and in situ breast cancers were observed and pT1 cases accounted for 44.4{\%}. Nodal involvement was present in 41.5{\%} of invasive cancers. A surgical treatment was performed in 1213 patients (96.7{\%}). Axillary dissection was reported in 1080 cases, 820 of them (76.6{\%}) having 10 or more lymph nodes examined. Radical mastectomy accounted for 74{\%} of the 458 breast cancers diagnosed in 1990 and 31.6{\%} of the eligible cases were conservatively treated. Conclusions: Cancer registries should be encouraged to report data on stage distribution in breast cancer (and in other malignancies). This practice could improve international comparisons and give an essential contribution to studies on survival, screening programs and quality of care.",
keywords = "breast cancer, cancer registries, staging",
author = "S. Rodella and M. Turazza and C. Picoco and F. Stanzial and F. Bonetti and Molino, {A. M.} and Donati, {L. F.} and E. Buongiorno and G. Calabrese and P. Castelli and M. Lestani and F. Marino and R. Mencarelli and G. Pelosi",
year = "1994",
language = "English",
volume = "80",
pages = "263--268",
journal = "Tumori",
issn = "0300-8916",
publisher = "SAGE Publications Ltd",
number = "4",

}

TY - JOUR

T1 - pTNM stage distribution in breast cancer

T2 - A population-based survey in northern Italy

AU - Rodella, S.

AU - Turazza, M.

AU - Picoco, C.

AU - Stanzial, F.

AU - Bonetti, F.

AU - Molino, A. M.

AU - Donati, L. F.

AU - Buongiorno, E.

AU - Calabrese, G.

AU - Castelli, P.

AU - Lestani, M.

AU - Marino, F.

AU - Mencarelli, R.

AU - Pelosi, G.

PY - 1994

Y1 - 1994

N2 - Aims and background: The role of distribution by stage at diagnosis in breast cancer has been considered in many studies, with particular regard to evaluation of prognosis, impact of screening programs and quality of care. Nevertheless, international comparisons of descriptive data can be hampered by lack of homogeneity in staging methods. The TNM is presently the most common staging system used all over the world, although some criticism have been raised recently against its pragmatic value. The present study reports a population-based survey of pathologic TNM distribution in incident cases of female breast cancer in the Verona province, a geographical area of northern Italy covered by cancer registration. Methods: All histologically proven incident cases of breast cancer were identified in the study period 1988-1990 and classified as for tumor size and nodal involvement according to the pathological TNM criteria. The type of surgical treatment was also registered for all cases diagnosed in 1990. Results: one thousand two hundreds and fifty-four invasive and in situ breast cancers were observed and pT1 cases accounted for 44.4%. Nodal involvement was present in 41.5% of invasive cancers. A surgical treatment was performed in 1213 patients (96.7%). Axillary dissection was reported in 1080 cases, 820 of them (76.6%) having 10 or more lymph nodes examined. Radical mastectomy accounted for 74% of the 458 breast cancers diagnosed in 1990 and 31.6% of the eligible cases were conservatively treated. Conclusions: Cancer registries should be encouraged to report data on stage distribution in breast cancer (and in other malignancies). This practice could improve international comparisons and give an essential contribution to studies on survival, screening programs and quality of care.

AB - Aims and background: The role of distribution by stage at diagnosis in breast cancer has been considered in many studies, with particular regard to evaluation of prognosis, impact of screening programs and quality of care. Nevertheless, international comparisons of descriptive data can be hampered by lack of homogeneity in staging methods. The TNM is presently the most common staging system used all over the world, although some criticism have been raised recently against its pragmatic value. The present study reports a population-based survey of pathologic TNM distribution in incident cases of female breast cancer in the Verona province, a geographical area of northern Italy covered by cancer registration. Methods: All histologically proven incident cases of breast cancer were identified in the study period 1988-1990 and classified as for tumor size and nodal involvement according to the pathological TNM criteria. The type of surgical treatment was also registered for all cases diagnosed in 1990. Results: one thousand two hundreds and fifty-four invasive and in situ breast cancers were observed and pT1 cases accounted for 44.4%. Nodal involvement was present in 41.5% of invasive cancers. A surgical treatment was performed in 1213 patients (96.7%). Axillary dissection was reported in 1080 cases, 820 of them (76.6%) having 10 or more lymph nodes examined. Radical mastectomy accounted for 74% of the 458 breast cancers diagnosed in 1990 and 31.6% of the eligible cases were conservatively treated. Conclusions: Cancer registries should be encouraged to report data on stage distribution in breast cancer (and in other malignancies). This practice could improve international comparisons and give an essential contribution to studies on survival, screening programs and quality of care.

KW - breast cancer

KW - cancer registries

KW - staging

UR - http://www.scopus.com/inward/record.url?scp=0028135640&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028135640&partnerID=8YFLogxK

M3 - Article

C2 - 7974796

AN - SCOPUS:0028135640

VL - 80

SP - 263

EP - 268

JO - Tumori

JF - Tumori

SN - 0300-8916

IS - 4

ER -