Pubertal growth and final height in children with chronic renal failure on conservative treatment

Roberto Rusconi, Aldo Appiani, Valeria Daccò, Gianluigi Ardissino, Sara Testa, Vittorio Carnelli

Research output: Contribution to journalArticlepeer-review

Abstract

In order to evaluate the pattern of pubertal growth in children with chronic renal failure (CRF) and its impact on the progression of renal impairment, the auxological data relating to ten boys and five girls with CRF were collected from the beginning to the end of puberty and compared with creatinine clearance (CCr) over the same period. The progression of renal impairment was evaluated as a regression line by plotting CCr by age before and after puberty. The magnitude (10.6 cm/year in males and 10.1 cm/year in females) and timing of peak height velocity (PHV) (13.6 and 11.3 years, respectively) were normal, as was the duration of puberty calculated as the interval between PHV and final height (FH). The slope of the mean regression line during the 5 years before and after PHV was respectively -1.1 ± 4.2 and -3.7 ± 3.2 (p

Original languageEnglish
Pages (from-to)271-276
Number of pages6
JournalJournal of Pediatric Endocrinology and Metabolism
Volume16
Issue numberSUPPL. 2
Publication statusPublished - 2003

Keywords

  • Chronic pediatric disease
  • Chronic renal failure
  • Delayed puberty
  • Pubertal development

ASJC Scopus subject areas

  • Endocrinology
  • Pediatrics, Perinatology, and Child Health

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