Pudendal Neuralgia: A New Option for Treatment? Preliminary Results on Feasibility and Efficacy

Marco Venturi, Paolo Boccasanta, Bruno Lombardi, Max Brambilla, Ettore Contessini Avesani, Contardo Vergani

Research output: Contribution to journalArticlepeer-review


Objective: The aim of this prospective study was to investigate the feasibility and report the short-term results of a new procedure for treatment of pudendal neuralgia, consisting of transperineal injections of autologous adipose tissue with stem cells along the Alcock's canal. Methods: Fifteen women with pudendal neuralgia not responsive to 3-months medical therapy were examined clinically, with VAS score, validated SF-36 questionnaire, and pudendal nerve motor terminal latency (PNMTL). These patients were submitted to pudendal nerve lipofilling. Clinical examinations with VAS, SF36, and PNTML were scheduled during 12 months follow-up, with the incidence of pain recurrence (VAS > 5) as primary outcome measure. Appropriate tests were used for statistics. Results: All patients had preoperative increase of pudendal nerve latencies. Twelve patients completed the follow-up protocol. There was no mortality, and no complications. Two patients had no pain improvement and continued to use analgesic drugs. At 12 months VAS significantly improved (3.2±0.6 vs 8.1±0.9, P

Original languageEnglish
Pages (from-to)1475-1481
Number of pages7
JournalPain Medicine (United States)
Issue number8
Publication statusPublished - Aug 1 2015


  • Lipofilling
  • Pudendal Neuralgia
  • Stem Cells

ASJC Scopus subject areas

  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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