TY - JOUR
T1 - Pulmonary arterial compliance and exercise capacity after pulmonary endarterectomy
AU - Ghio, Stefano
AU - Morsolini, Marco
AU - Corsico, Angelo
AU - Klersy, Catherine
AU - Mattiucci, Gabriella
AU - Raineri, Claudia
AU - Scelsi, Laura
AU - Vistarini, Nicola
AU - Visconti, Luigi Oltrona
AU - D'Armini, Andrea Maria
PY - 2014/5/1
Y1 - 2014/5/1
N2 - Patients with chronic thromboembolic pulmonary hypertension (CTEPH), despite successful pulmonary endarterectomy (PEA), can continue to suffer from a limitation in exercise capacity. The objective of this study was to assess whether pulmonary arterial compliance is a predictor of exercise capacity after PEA. Right heart haemodynamics, treadmill incremental exercise test, spirometry, carbon monoxide transfer factor, arterial blood gas and echocardiographic examinations were retrospectively analysed in a population of CTEPH patients who underwent PEA at a single centre. Baseline and 3-month haemodynamic data were available in 296 patients; 5-year follow-up data were available in 68 patients. In a multivariable model the following parameters were found to be independent predictors of exercise capacity after surgery: age, sex, pulmonary arterial compliance, tricuspid annular plane excursion, arterial oxygen tension and carbon monoxide transfer factor (p
AB - Patients with chronic thromboembolic pulmonary hypertension (CTEPH), despite successful pulmonary endarterectomy (PEA), can continue to suffer from a limitation in exercise capacity. The objective of this study was to assess whether pulmonary arterial compliance is a predictor of exercise capacity after PEA. Right heart haemodynamics, treadmill incremental exercise test, spirometry, carbon monoxide transfer factor, arterial blood gas and echocardiographic examinations were retrospectively analysed in a population of CTEPH patients who underwent PEA at a single centre. Baseline and 3-month haemodynamic data were available in 296 patients; 5-year follow-up data were available in 68 patients. In a multivariable model the following parameters were found to be independent predictors of exercise capacity after surgery: age, sex, pulmonary arterial compliance, tricuspid annular plane excursion, arterial oxygen tension and carbon monoxide transfer factor (p
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U2 - 10.1183/09031936.00195313
DO - 10.1183/09031936.00195313
M3 - Article
C2 - 24435007
AN - SCOPUS:84899890473
VL - 43
SP - 1403
EP - 1409
JO - European Journal of Respiratory Diseases
JF - European Journal of Respiratory Diseases
SN - 0903-1936
IS - 5
ER -