Pulmonary arterial compliance and exercise capacity after pulmonary endarterectomy

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Abstract

Patients with chronic thromboembolic pulmonary hypertension (CTEPH), despite successful pulmonary endarterectomy (PEA), can continue to suffer from a limitation in exercise capacity. The objective of this study was to assess whether pulmonary arterial compliance is a predictor of exercise capacity after PEA. Right heart haemodynamics, treadmill incremental exercise test, spirometry, carbon monoxide transfer factor, arterial blood gas and echocardiographic examinations were retrospectively analysed in a population of CTEPH patients who underwent PEA at a single centre. Baseline and 3-month haemodynamic data were available in 296 patients; 5-year follow-up data were available in 68 patients. In a multivariable model the following parameters were found to be independent predictors of exercise capacity after surgery: age, sex, pulmonary arterial compliance, tricuspid annular plane excursion, arterial oxygen tension and carbon monoxide transfer factor (p

Original languageEnglish
Pages (from-to)1403-1409
Number of pages7
JournalEuropean Respiratory Journal
Volume43
Issue number5
DOIs
Publication statusPublished - May 1 2014

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Medicine(all)

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