Pulmonary emphysema not combined with lung fibrosis in systemic sclerosis

Andrea Franconeri, Emiliano Marasco, Roberto Dore, Veronica Codullo, Fabrizio Calliada, Eliana Disabella, Federica Meloni, Giovanni Zanframundo, Carlomaurizio Montecucco, Adele Valentini, Lorenzo Cavagna

Research output: Contribution to journalArticlepeer-review

Abstract

Interstitial Lung Disease (ILD) is a common finding of Systemic Sclerosis (SSc) mainly presenting in the form of Nonspecific Interstitial Pneumonia (NSIP) and deeply affecting patients’ prognosis. Beside NSIP, other types of ILD have been reported. The most recently described pattern is the so-called Combined-pulmonary emphysema and lung fibrosis, characterized by the coexistence of both upper lobes centrilobular and paraseptal emphysema and lower lobes ILD. We presented three cases of patients with SSc, in which High Resolution Computed Tomography examinations showed emphysema with atypical distribution and radiological presentation, without or with mild signs of fibrosing lung disease, that stabilized after immunosuppressive treatment.

Original languageEnglish
Article number105816
JournalRespiratory Medicine
Volume160
DOIs
Publication statusPublished - Nov 1 2019

Keywords

  • Emphysema
  • High Resolution Computed Tomography
  • Interstitial lung disease
  • Systemic Sclerosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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