Il granuloma eosinofilo polmonare dell'adulto. Contributo casistico e revisione della letteratura.

Translated title of the contribution: Pulmonary eosinophilic granuloma in adults. Case histories and a review of the literature

M. Zompatori, G. Gavelli, A. Bernasconi, M. Fabbri, C. Sturani, V. Galavotti

Research output: Contribution to journalArticlepeer-review

Abstract

Histiocytosis X is a disease of unknown origin which usually affects multiple organs, including the lung. The age of onset, the clinical course and the pattern of spread allow a distinction to be made between 3 varieties: Letterer-Siwe, Hand-Schüller-Christian and eosinophilic granuloma. The latter form, in adult patients, may predominantly or solely affect the lungs. The authors reviewed clinical, radiographic and CT findings of 7 adult patients with pulmonary eosinophilic granuloma, picked out of a series of 265 cases of interstitial lung pathology, diagnosed since 1973. Typical pulmonary involvement is bilateral, symmetrical and predominates in the upper areas. Honeycomb pattern was found in 1 patient at the onset of symptoms, and in 2 cases during the follow-up, without severe reduction in pulmonary volumes. Pneumothorax was observed in 3 cases and bone lesions in 2. CT added new and important informations such as presence, size and wall thickness of "cystic" lesions. New laboratory tests and bronchoalveolar lavage demonstrated minor diagnostic usefulness than radiological findings. The authors conclude by discussing such problems as prognostic factors and differential diagnosis.

Translated title of the contributionPulmonary eosinophilic granuloma in adults. Case histories and a review of the literature
Original languageItalian
Pages (from-to)347-353
Number of pages7
JournalRadiologia Medica
Volume77
Issue number4
Publication statusPublished - Apr 1989

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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