Abstract
Two women, 65 and 55 years old, with metastatic malignant melanoma, were treated with low doses of BCNU for a short period (six and three months, total dose 2500 and 2000 mg). Both patients developed pulmonary fibrosis, which was visible in postmortem examination. In the first woman, lesion development was so widespread as to be considered responsible for death. Because chest x-ray before tractment was not abnormal, the authors consider BCNU capable of inducing the lesion.
| Original language | English |
|---|---|
| Pages (from-to) | 1311-1314 |
| Number of pages | 4 |
| Journal | Cancer |
| Volume | 45 |
| Issue number | 6 |
| Publication status | Published - 1980 |
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ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Pulmonary fibrosis following low-dose 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) therapy. / Melato, M.; Tuveri, G.
In: Cancer, Vol. 45, No. 6, 1980, p. 1311-1314.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pulmonary fibrosis following low-dose 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) therapy
AU - Melato, M.
AU - Tuveri, G.
PY - 1980
Y1 - 1980
N2 - Two women, 65 and 55 years old, with metastatic malignant melanoma, were treated with low doses of BCNU for a short period (six and three months, total dose 2500 and 2000 mg). Both patients developed pulmonary fibrosis, which was visible in postmortem examination. In the first woman, lesion development was so widespread as to be considered responsible for death. Because chest x-ray before tractment was not abnormal, the authors consider BCNU capable of inducing the lesion.
AB - Two women, 65 and 55 years old, with metastatic malignant melanoma, were treated with low doses of BCNU for a short period (six and three months, total dose 2500 and 2000 mg). Both patients developed pulmonary fibrosis, which was visible in postmortem examination. In the first woman, lesion development was so widespread as to be considered responsible for death. Because chest x-ray before tractment was not abnormal, the authors consider BCNU capable of inducing the lesion.
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UR - http://www.scopus.com/inward/citedby.url?scp=0018868157&partnerID=8YFLogxK
M3 - Article
C2 - 7357522
AN - SCOPUS:0018868157
VL - 45
SP - 1311
EP - 1314
JO - Cancer
JF - Cancer
SN - 0008-543X
IS - 6
ER -