Pulmonary function in patients surviving to COVID-19 pneumonia

Alessia Fumagalli; Clementina Misuraca; Achille Bianchi; Noemi Borsa; Simone Limonta; Sveva Maggiolini; Daniela Rita Bonardi; Andrea Corsonello; Mirko Di Rosa; Luca Soraci; Fabrizia Lattanzio; Daniele Colombo

doi:10.1007/s15010-020-01474-9

Pulmonary function in patients surviving to COVID-19 pneumonia

Alessia Fumagalli, Clementina Misuraca, Achille Bianchi, Noemi Borsa, Simone Limonta, Sveva Maggiolini, Daniela Rita Bonardi, Andrea Corsonello, Mirko Di Rosa, Luca Soraci, Fabrizia Lattanzio, Daniele Colombo

Istituto Nazionale di Riposo e Cura per Anziani V.E. II

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: The aim of our study was to assess respiratory function at the time of clinical recovery and 6 weeks after discharge in patients surviving to COVID-19 pneumonia. Methods: Our case series consisted of 13 patients with COVID-19 pneumonia. Results: At the time of clinical recovery, FEV1 (2.07 ± 0.72 L) and FVC (2.25 ± 0.86 L) were lower compared to lower limit of normality (LLN) values (2.56 ± 0.53 L, p = 0.004, and 3.31 ± 0.65 L, p < 0.001, respectively), while FEV1/FVC (0.94 ± 0.07) was higher compared to upper limit of normality (ULN) values (0.89 ± 0.01, p = 0.029). After 6 weeks pulmonary function improved but FVC was still lower than ULN (2.87 ± 0.81, p = 0.014). Conclusion: These findings suggest that COVID-19 pneumonia may result in clinically relevant alterations in pulmonary function tests, with a mainly restrictive pattern.

Original language	English
Pages (from-to)	153-157
Number of pages	5
Journal	Infection
Volume	49
Issue number	1
DOIs	https://doi.org/10.1007/s15010-020-01474-9
Publication status	Published - Feb 2021

Keywords

COVID-19
Pneumonia
Spirometry

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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Pulmonary function in patients surviving to COVID-19 pneumonia. / Fumagalli, Alessia ; Misuraca, Clementina; Bianchi, Achille; Borsa, Noemi; Limonta, Simone; Maggiolini, Sveva ; Bonardi, Daniela Rita ; Corsonello, Andrea ; Di Rosa, Mirko; Soraci, Luca; Lattanzio, Fabrizia ; Colombo, Daniele.

In: Infection, Vol. 49, No. 1, 02.2021, p. 153-157.

Research output: Contribution to journal › Article › peer-review

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AU - Bianchi, Achille

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AU - Bonardi, Daniela Rita

AU - Corsonello, Andrea

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AU - Lattanzio, Fabrizia

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