Granuloma jalinizzante del polmone. Studio clinico-patologico di 2 casi, con alcune originali osservazioni ultrastrutturali e revisione della letteratura

Translated title of the contribution: Pulmonary hyalinizing granuloma. Clinicopathologic study of 2 cases, with some original ultrastructural observations and review of the literature

G. Vezzani, Alberto Cavazza, G. Rossi, G. Pasquinelli, P. Avanzini, S. Asioli, S. Piana, M. Chilosi

Research output: Contribution to journalArticle

Abstract

Aim: To report the clinical, histological, immunohistochemical and ultrastructural features of 2 new cases of pulmonary hyalinizing granuloma. Results: Both patients were males: one, 72-year-old with retroperitoneal fibrosis, was asymptomatic, while the other, 67-year-old, presented with non productive cough. In both cases, a chest x-ray showed a solitary pulmonary nodule. Microscopically, the nodules were well circumscribed and composed of lamellae of hyalinized collagen. At the periphery, a more cellular rim consisting of lymphocytes, plasma cells and myofibroblasts was present. Immunohistochemical and ultrastructural examinations revealed myofibroblastic elements actively synthesizing collagen fibrils.

Translated title of the contributionPulmonary hyalinizing granuloma. Clinicopathologic study of 2 cases, with some original ultrastructural observations and review of the literature
Original languageItalian
Pages (from-to)23-28
Number of pages6
JournalPathologica
Volume96
Issue number1
Publication statusPublished - Feb 2004

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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