Le metastasi polmonari da carcinoma basocellulare della cute. Presentazione di tre casi.

Translated title of the contribution: Pulmonary metastasis of basal cell carcinoma of the skin. 3 case reports

P. P. Brega Massone, C. Lequaglie, F. Ferro, G. Gallino, B. Conti, I. Cataldo

Research output: Contribution to journalArticle

Abstract

The Authors describe three cases of lung metastasis from a basal cell carcinoma of the skin observed in the Department of Thoracic Surgery of the National Cancer Institute in Milan. The incidence of this rare occurrence reported in the literature is approximately 0.1%, The aim of the study was to evaluate the therapeutic treatment adopted in these unusual situations. In all cases the primary basal cell carcinoma of the skin was located in the head. All three patients had several local and regional recurrences and underwent multiple surgical excisions and subsequent plastic procedures. In each case complementary radiotherapy was implemented. The metastases appeared in the lung 9, 17 and 21 years, respectively, after onset of the primary tumour as bilateral nodules in two cases and as a single nodule in one. Curative surgery was possible only in one subject, consisting in a bilateral metastasectomy via a midline sternotomy, with 5-year survival. Surgery was withheld in the other two subjects owing to advanced age and the presence of bilateral nodules with concomitant bone metastasis, respectively. Both were treated by chemotherapy and the patient with synchronous bone metastasis also received radiotherapy. The elderly subject died after six months, and the other patient after 19 months despite partial remission of disease. In our experience, curative therapy proves difficult due to multiple metastases. In the literature there are few reports regarding this rare type of metastatic lung disease, but surgical intervention would appear to be the therapy offering the best chance of long-term survival while chemotherapy constitutes the second-choice treatment.

Original languageItalian
Pages (from-to)165-169
Number of pages5
JournalChirurgia Italiana
Volume52
Issue number2
Publication statusPublished - Mar 2000

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Basal Cell Carcinoma
Neoplasm Metastasis
Lung
Skin
Radiotherapy
Metastasectomy
Therapeutics
Bone and Bones
Drug Therapy
Sternotomy
Survival
National Cancer Institute (U.S.)
Lung Diseases
Thoracic Surgery
Head
Recurrence
Incidence
Neoplasms

ASJC Scopus subject areas

  • Surgery

Cite this

Brega Massone, P. P., Lequaglie, C., Ferro, F., Gallino, G., Conti, B., & Cataldo, I. (2000). Le metastasi polmonari da carcinoma basocellulare della cute. Presentazione di tre casi. Chirurgia Italiana, 52(2), 165-169.

Le metastasi polmonari da carcinoma basocellulare della cute. Presentazione di tre casi. / Brega Massone, P. P.; Lequaglie, C.; Ferro, F.; Gallino, G.; Conti, B.; Cataldo, I.

In: Chirurgia Italiana, Vol. 52, No. 2, 03.2000, p. 165-169.

Research output: Contribution to journalArticle

Brega Massone, PP, Lequaglie, C, Ferro, F, Gallino, G, Conti, B & Cataldo, I 2000, 'Le metastasi polmonari da carcinoma basocellulare della cute. Presentazione di tre casi.', Chirurgia Italiana, vol. 52, no. 2, pp. 165-169.
Brega Massone PP, Lequaglie C, Ferro F, Gallino G, Conti B, Cataldo I. Le metastasi polmonari da carcinoma basocellulare della cute. Presentazione di tre casi. Chirurgia Italiana. 2000 Mar;52(2):165-169.
Brega Massone, P. P. ; Lequaglie, C. ; Ferro, F. ; Gallino, G. ; Conti, B. ; Cataldo, I. / Le metastasi polmonari da carcinoma basocellulare della cute. Presentazione di tre casi. In: Chirurgia Italiana. 2000 ; Vol. 52, No. 2. pp. 165-169.
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