TY - JOUR
T1 - Pulmonary sequestration
T2 - A 131I whole body scintigraphy false-positive result
AU - Spinapolice, Elena Giulia
AU - Chytiris, S.
AU - Fuccio, C.
AU - Leporati, P.
AU - Volpato, G.
AU - Villani, L.
AU - Trifirò, G.
AU - Chiovato, L.
PY - 2014
Y1 - 2014
N2 - A 35-year-old woman affected by a well-differentiated papillary thyroid carcinoma was referred to our hospital to perform a 131Iodine ( 131I) whole body scintigraphy for restaging purpose. The patient had been previously treated with total thyroidectomy and three subsequent doses of 131I for the ablation of a remnant jugular tissue and a suspected metastatic focus at the superior left hemi-thorax. In spite of the previous treatments with 131I, planar and tomographic images showed the persistence of an area of increased uptake at the superior left hemi-thorax. This finding prompted the surgical resection of the lesion. Histological examination of the surgical specimen showed the presence of a pulmonary tissue consistent with pulmonary sequestration. Even though rare, pulmonary sequestration should be included in the potential causes of false-positive results of radioiodine scans.
AB - A 35-year-old woman affected by a well-differentiated papillary thyroid carcinoma was referred to our hospital to perform a 131Iodine ( 131I) whole body scintigraphy for restaging purpose. The patient had been previously treated with total thyroidectomy and three subsequent doses of 131I for the ablation of a remnant jugular tissue and a suspected metastatic focus at the superior left hemi-thorax. In spite of the previous treatments with 131I, planar and tomographic images showed the persistence of an area of increased uptake at the superior left hemi-thorax. This finding prompted the surgical resection of the lesion. Histological examination of the surgical specimen showed the presence of a pulmonary tissue consistent with pulmonary sequestration. Even though rare, pulmonary sequestration should be included in the potential causes of false-positive results of radioiodine scans.
KW - Pulmonary disease
KW - Pulmonary sequestration
KW - Thyroid carcinoma
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U2 - 10.1007/s12149-014-0838-5
DO - 10.1007/s12149-014-0838-5
M3 - Article
C2 - 24658773
AN - SCOPUS:84906354527
VL - 28
SP - 683
EP - 687
JO - Annals of Nuclear Medicine
JF - Annals of Nuclear Medicine
SN - 0914-7187
IS - 7
ER -