Pulmonary sequestration: A 131I whole body scintigraphy false-positive result

Elena Giulia Spinapolice, S. Chytiris, C. Fuccio, P. Leporati, G. Volpato, L. Villani, G. Trifirò, L. Chiovato

Research output: Contribution to journalArticlepeer-review


A 35-year-old woman affected by a well-differentiated papillary thyroid carcinoma was referred to our hospital to perform a 131Iodine ( 131I) whole body scintigraphy for restaging purpose. The patient had been previously treated with total thyroidectomy and three subsequent doses of 131I for the ablation of a remnant jugular tissue and a suspected metastatic focus at the superior left hemi-thorax. In spite of the previous treatments with 131I, planar and tomographic images showed the persistence of an area of increased uptake at the superior left hemi-thorax. This finding prompted the surgical resection of the lesion. Histological examination of the surgical specimen showed the presence of a pulmonary tissue consistent with pulmonary sequestration. Even though rare, pulmonary sequestration should be included in the potential causes of false-positive results of radioiodine scans.

Original languageEnglish
Pages (from-to)683-687
Number of pages5
JournalAnnals of Nuclear Medicine
Issue number7
Publication statusPublished - 2014


  • Pulmonary disease
  • Pulmonary sequestration
  • Thyroid carcinoma

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)


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