Valvuloplastica polmonare in età pediatrica: risultati immediati e follow-up a lungo termine.

Translated title of the contribution: Pulmonary valvuloplasty in childhood: the immediate results and long-term follow-up

G. Santoro, R. Formigari, L. Pasquini, A. De Zorzi, L. Ballerini

Research output: Contribution to journalArticlepeer-review


BACKGROUND. Pulmonary balloon valvuloplasty is the treatment of choice of pulmonary valve stenosis, but early results and long-term follow-up in a numerous and homogeneous pediatric population are poorly known. MATERIAL AND METHODS. From April 1984 to April 1994, 202 valvuloplastic procedures were performed in 197 patients (age 52.5 +/- 150 months). Hemodynamic data were analysed according with valvular morphology and patient's age at procedure. During a follow-up period of 50 +/- 38 months, clinical and instrumental data were collected. RESULTS. After pulmonary valvuloplasty RV pressure decreased from 86 +/- 28 to 41 +/- 21 mm Hg (p <0.001), transvalvular pressure gradient from 67 +/- 27 to 24 +/- 14 mm Hg (p <0.001) and RV/LV pressure ratio from 1.01 +/- 0.29 to 0.53 +/- 0.19 (p <0.001). Overall success rate was 95% (187/197 patients). Pulmonary valve dysplasia and/or annulus hypoplasia significantly influenced the efficacy of the procedure and/or the recurrence of valvar stenosis (18.8% vs 2.7%, p <0.01). During the follow-up period, clinical examination was unremarkable, and transvalvular pressure gradient did not change (23 +/- 9 vs 24 +/- 6 mm Hg at discharge, p = NS). Freedom from restenosis was 98% at 3 years and 96% at 5 and 10 years. CONCLUSIONS. Pulmonary balloon valvuloplasty is a safe, effective and possibly definitive treatment for isolated pulmonary valve stenosis in infants and children. Age at valvuloplasty does not influence the success of the procedure, as opposed to valvular dysplasia and/or annulus hypoplasia that positively relate to the need of surgical valvotomy and/or the recurrence of stenosis during a long-term follow-up. In conclusion, prognosis of the majority of infants and children after a successful valvuloplasty is excellent during a long-term follow-up period.

Translated title of the contributionPulmonary valvuloplasty in childhood: the immediate results and long-term follow-up
Original languageItalian
Pages (from-to)139-147
Number of pages9
JournalGiornale Italiano di Cardiologia
Issue number2
Publication statusPublished - Feb 1995

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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