'Pure' meningeal carcinomatosis as the autopsy-proven sole manifestation of an undetected cancer

A. Leonardi, N. Dagnino, M. Farinelli, C. Gambini, G. Ribizzi, A. Schenone, G. L. Mancardi

Research output: Contribution to journalArticlepeer-review

Abstract

Meningeal carcinomatosis (MC) was diagnosed in a 37-year-old woman, based on the finding of neoplastic cells in the cerebrospinal fluid. The patient had no relevant antecedent except the resection of a breast 'nodule' at the age of 20. No primary cancer nor other metastases were detected, even at autopsy. Histopathology, immunocytochemistry and electron microscopy confirmed pure leptomeningeal infiltration by poorly differentiated adenoepithelial cancer. This case includes several unusual features and raises the possibility of an extremely long-lasting interval between an unrecognized primary (breast?) carcinoma and MC.

Original languageEnglish
Pages (from-to)60-63
Number of pages4
JournalClinical Neuropathology
Volume11
Issue number2
Publication statusPublished - 1992

ASJC Scopus subject areas

  • Clinical Neurology
  • Pathology and Forensic Medicine
  • Neuroscience(all)

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