Purely off-clamp robotic partial nephrectomy: Preliminary 3-year oncological and functional outcomes

Giuseppe Simone, Leonardo Misuraca, Gabriele Tuderti, Francesco Minisola, Mariaconsiglia Ferriero, Giuseppe Romeo, Manuela Costantini, Samer F. Al-Rawashdah, Salvatore Guaglianone, Michele Gallucci

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objectives: To describe our surgical technique and to report perioperative, 3-year oncological and functional outcomes of a single-center series of purely off-clamp robotic partial nephrectomy. Methods: A prospective renal cancer institutional database was queried, and data of consecutive patients treated with purely off-clamp robotic partial nephrectomy between 2010 and 2015 in a high-volume center were collected. Perioperative complications, and 3-year oncological and functional outcomes were assessed. Univariable and multivariable analyses were carried out to identify independent predictors of renal function deterioration. Results: Out of 308 patients treated, 41 (13.3%) experienced perioperative complications, 2.9% of which were Clavien grade ≥3. The 3-year local recurrence-free survival and renal cell carcinoma-specific survival rates were 99.5% and 97.9%, respectively. No patient with preoperative chronic kidney disease stage ≤3B developed severe renal function deterioration (chronic kidney disease stage 4) at 1-year follow up. At multivariable analysis, preoperative estimated glomerular filtration rate (P = 0.005) was the only independent predictor of a new-onset chronic kidney disease stage ≥3 in patients with preoperative chronic kidney disease stages 1 or 2. Conclusions: Off-clamp robotic partial nephrectomy is a safe surgical approach in tertiary referral centers, with adequate oncological outcomes and negligible impact on renal function.

Original languageEnglish
JournalInternational Journal of Urology
DOIs
Publication statusAccepted/In press - Jan 1 2018

Fingerprint

Robotics
Nephrectomy
Chronic Renal Insufficiency
Kidney
Kidney Neoplasms
Glomerular Filtration Rate
Renal Cell Carcinoma
Tertiary Care Centers
Survival Rate
Databases
Recurrence
Survival

Keywords

  • Off-clamp
  • Oncological outcomes
  • Partial nephrectomy
  • Renal function
  • Robotic

ASJC Scopus subject areas

  • Urology

Cite this

Purely off-clamp robotic partial nephrectomy : Preliminary 3-year oncological and functional outcomes. / Simone, Giuseppe; Misuraca, Leonardo; Tuderti, Gabriele; Minisola, Francesco; Ferriero, Mariaconsiglia; Romeo, Giuseppe; Costantini, Manuela; Al-Rawashdah, Samer F.; Guaglianone, Salvatore; Gallucci, Michele.

In: International Journal of Urology, 01.01.2018.

Research output: Contribution to journalArticle

Simone, Giuseppe ; Misuraca, Leonardo ; Tuderti, Gabriele ; Minisola, Francesco ; Ferriero, Mariaconsiglia ; Romeo, Giuseppe ; Costantini, Manuela ; Al-Rawashdah, Samer F. ; Guaglianone, Salvatore ; Gallucci, Michele. / Purely off-clamp robotic partial nephrectomy : Preliminary 3-year oncological and functional outcomes. In: International Journal of Urology. 2018.
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