Purification and characterization of bovine and ovine submaxillary mucins

Guido Tettamanti, Ward Pigman

Research output: Contribution to journalArticle

Abstract

The procedure of Tsuiki et al. for the isolation of bovine submaxillary mucin was modified but gave a product (BSM-T) very similar to that reported earlier. When applied to ovine submaxillary glands, it gave a very similar product (OSM-T) with a somewhat simpler composition. When treated with hydroxyapatite gel, a minor component (5-15%) was separated from each of both the ovine and bovine products. The major mucins had compositions similar to those of the untreated products. The minor mucins had larger amounts of protein, l-fucose, and d-galactose, and of the "minor" amino acids. The molecular weights of the major mucins were about 4 × 105. A possible physiological role is suggested.

Original languageEnglish
Pages (from-to)41-50
Number of pages10
JournalArchives of Biochemistry and Biophysics
Volume124
Issue numberC
Publication statusPublished - 1968

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ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

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