Purines and pyrimidines determination in urine using high-performance liquid chromatography

G. Minniti, U. Caruso, R. Cerone, E. De Toni

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Single purine and pirimidine bases are involved in two fundamental metabolic pathways that lead to formation of the building stones of DNA and RNA. Purine and pyrimidine nucleotides are also critically important metabolites in many cellular functions. The main breakdown of purines and pyrimidines produces uric acid and B-minoacids, respectively. Therefore, the study of purine and pirimidine compounds in body fluid has high clinical relevance. We report, in this work, our experience in purines and pyrimidines determination in urine from children presenting with a clinical picture suggesting an inborn these pathways.

Original languageEnglish
Pages (from-to)843-848
Number of pages6
JournalAdvances in Experimental Medicine and Biology
Volume431
Publication statusPublished - 1998

Fingerprint

Pyrimidines
Purines
High performance liquid chromatography
High Pressure Liquid Chromatography
Urine
Pyrimidine Nucleotides
Purine Nucleotides
Body fluids
Body Fluids
Metabolites
Metabolic Networks and Pathways
Uric Acid
RNA
DNA
purine

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Purines and pyrimidines determination in urine using high-performance liquid chromatography. / Minniti, G.; Caruso, U.; Cerone, R.; De Toni, E.

In: Advances in Experimental Medicine and Biology, Vol. 431, 1998, p. 843-848.

Research output: Contribution to journalArticle

Minniti, G. ; Caruso, U. ; Cerone, R. ; De Toni, E. / Purines and pyrimidines determination in urine using high-performance liquid chromatography. In: Advances in Experimental Medicine and Biology. 1998 ; Vol. 431. pp. 843-848.
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