Abstract
Multiple sclerosis (MS) patients frequently develop some form of ocular motor dysfunction during the disease. In previous studies, ocular motor abnormalities were found to correlate with clinical disability and with impaired cognitive performance. The objective of this study was to assess the pursuit ocular movement (POM) frequency in relapsing-remitting (RR) and secondary progressive (SP) MS patients by using a vision-based non-intrusive eye tracker. POM frequency was significantly lower (p <0.001) in MS patients compared to normal controls. No differences between RR and SP-MS patients and no correlation between POM and expanded disability status scale (EDSS) score were found. This exploratory study suggests that our vision-based system is a new simple non-intrusive method showing impairment of POM values in MS patients, even in the absence of association with clinical disability (EDSS). Future works on larger cohorts of MS patients might validate this eye tracking in MS clinical practice.
| Original language | English |
|---|---|
| Pages (from-to) | 67-71 |
| Number of pages | 5 |
| Journal | Neurological Sciences |
| Volume | 32 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Feb 2011 |
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Keywords
- Eye movements
- Multiple sclerosis
- Pursuit ocular movements
- Video-based eye-tracking system
ASJC Scopus subject areas
- Clinical Neurology
- Psychiatry and Mental health
- Dermatology
Cite this
Pursuit ocular movements in multiple sclerosis : A video-based eye-tracking study. / De Santi, Lorenzo; Lanzafame, Pietro; Spanò, Barbara; D'Aleo, Giangaetano; Bramanti, Alessia; Bramanti, Placido; Marino, Silvia.
In: Neurological Sciences, Vol. 32, No. 1, 02.2011, p. 67-71.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Pursuit ocular movements in multiple sclerosis
T2 - A video-based eye-tracking study
AU - De Santi, Lorenzo
AU - Lanzafame, Pietro
AU - Spanò, Barbara
AU - D'Aleo, Giangaetano
AU - Bramanti, Alessia
AU - Bramanti, Placido
AU - Marino, Silvia
PY - 2011/2
Y1 - 2011/2
N2 - Multiple sclerosis (MS) patients frequently develop some form of ocular motor dysfunction during the disease. In previous studies, ocular motor abnormalities were found to correlate with clinical disability and with impaired cognitive performance. The objective of this study was to assess the pursuit ocular movement (POM) frequency in relapsing-remitting (RR) and secondary progressive (SP) MS patients by using a vision-based non-intrusive eye tracker. POM frequency was significantly lower (p <0.001) in MS patients compared to normal controls. No differences between RR and SP-MS patients and no correlation between POM and expanded disability status scale (EDSS) score were found. This exploratory study suggests that our vision-based system is a new simple non-intrusive method showing impairment of POM values in MS patients, even in the absence of association with clinical disability (EDSS). Future works on larger cohorts of MS patients might validate this eye tracking in MS clinical practice.
AB - Multiple sclerosis (MS) patients frequently develop some form of ocular motor dysfunction during the disease. In previous studies, ocular motor abnormalities were found to correlate with clinical disability and with impaired cognitive performance. The objective of this study was to assess the pursuit ocular movement (POM) frequency in relapsing-remitting (RR) and secondary progressive (SP) MS patients by using a vision-based non-intrusive eye tracker. POM frequency was significantly lower (p <0.001) in MS patients compared to normal controls. No differences between RR and SP-MS patients and no correlation between POM and expanded disability status scale (EDSS) score were found. This exploratory study suggests that our vision-based system is a new simple non-intrusive method showing impairment of POM values in MS patients, even in the absence of association with clinical disability (EDSS). Future works on larger cohorts of MS patients might validate this eye tracking in MS clinical practice.
KW - Eye movements
KW - Multiple sclerosis
KW - Pursuit ocular movements
KW - Video-based eye-tracking system
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UR - http://www.scopus.com/inward/citedby.url?scp=79551586477&partnerID=8YFLogxK
U2 - 10.1007/s10072-010-0395-1
DO - 10.1007/s10072-010-0395-1
M3 - Article
VL - 32
SP - 67
EP - 71
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - 1
ER -