Pyothorax-associated lymphoma: Description of the first case detected in Italy

R. F. Frongillo, S. Ascani, S. A. Pileri, G. E. Crapa, E. Baltzaki, G. B. Bolis, F. Liberati

Research output: Contribution to journalArticlepeer-review


The clinical, histological and molecular findings observed in an Italian patient with malignant lymphoma and chronic pyothorax are described (pyothorax-associated lymphoma: PAL). Such a kind of neoplastic process characteristically develops a very long time (years or decades) after a therapeutic pneumothorax for tuberculosis. Latent EBV viral infection is demonstrated by the presence in the neoplastic cells of the EBV-related small RNAs EBER-1 and 2 along with the positivity for EBNA-2 and LMP-1. The present case is the first documented occurrence of PAL in Italy.

Original languageEnglish
Pages (from-to)172-177
Number of pages6
JournalMediterranean Journal of Infectious and Parasitic Diseases
Issue number4
Publication statusPublished - 1997


  • EBV
  • Malignant lymphoma
  • Pyothorax
  • Tuberculosis

ASJC Scopus subject areas

  • Microbiology (medical)


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