QT dispersion and left ventricular hypertrophy in elderly hypertensive and normotensive patients

Stavros Dimopoulos, Franco Nicosia, Paolo Donati, Paola Prometti, Massimiliano De Vecchi, Roberto Zulli, Vittorio Grassi

Research output: Contribution to journalArticle

Abstract

Inhomogeneity of ventricular repolarization as detected by QT dispersion may be a potential leading mechanism of sudden death in hypertensive and normotensive (age related) left ventricular hypertrophy. Aim of this study was to investigate QT dispersion, ventricular arrhythmias, and left ventricular mass index in elderly hypertensive and normotensive patients. Study population consisted of 60 consecutive patients (sex: 34 men/26 women; age: 63 ± 11 years) with essential arterial hypertension and 48 age and sex-matched control subjects (24 men/24 women; 64 ± 16 years). Measurements included QTc dispersion, ventricular arrhythmias, and left ventricular hypertrophy. Hypertensive patients had greater left ventricular mass index (P =.006) and higher QTc dispersion (P =.004) than controls. Left ventricular hypertrophy was diagnosed in 57 (31 men/26 women) of all subjects. These patients had higher blood pressure (P

Original languageEnglish
Pages (from-to)605-612
Number of pages8
JournalAngiology
Volume59
Issue number5
DOIs
Publication statusPublished - Oct 2008

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Keywords

  • Arterial hypertension
  • Elderly
  • Left ventricular hypertrophy
  • QT dispersion
  • Ventricular arrhythmias

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Dimopoulos, S., Nicosia, F., Donati, P., Prometti, P., De Vecchi, M., Zulli, R., & Grassi, V. (2008). QT dispersion and left ventricular hypertrophy in elderly hypertensive and normotensive patients. Angiology, 59(5), 605-612. https://doi.org/10.1177/0003319707310276