QTc interval and QTc dispersion during haemodiafiltration

Fulvio Floccari, Emanuele Aloisi, Lorena Nostro, Chiara Caccamo, Alessandra Crisafulli, Antonio Barillà, Carmela Aloisi, Adolfo Romeo, Francesco Corica, Riccardo Ientile, Nicola Frisina, Michele Buemi

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background and Aim: Our aim was to evaluate QTc interval and QTc dispersion in 27 end-stage renal disease (ESRD) patients undergoing Acetate Free Biofiltration (AFB) in order to ascertain any correlations between the electrrocardiographic (ECG) parameters, serum Na+, K+, Ca++, Mg++ and intraerythrocytic Mg++ (Mg++e) concentrations. All measures were made at to (session beginning), t1 (first hour), t2 (second hour), t3 (third hour), and t4 (session end). Results: Blood pressure, heart rate, bodyweight and total ultrafiltration in the three dialysis sessions were constant. A significant progressive increase occurred in serum Ca++ during the sessions, while there was a significant diminution in serum K+. The pattern for Mg++ concentrations in serum and erythrocytes differed: in serum it decreased, whereas Mg++e increased. At t4, the QTc interval was reduced to a significant extent with respect to the baseline value. QTc dispersion significantly increased at t1 without there being significant variations at other times with respect to t0. At t2, t3 and t4, values promptly returned to baseline levels. QTc had a negative correlation with serum Ca++ levels at t4. In contrast, an inverse correlation was found between QTc dispersion and serum K+ at t1. No other correlations could be found between any other electrolytes, QTc interval or QTc dispersion. Conclusion: In conclusion, the decrease observed in the QTc interval at the end of an AFB session was inversely related to serum Ca++ concentrations. Moreover, an increase in QTc dispersion occurred during the first hour of the session, and was negatively correlated with serum K+.

Original languageEnglish
Pages (from-to)335-340
Number of pages6
JournalNephrology
Volume9
Issue number6
DOIs
Publication statusPublished - Dec 2004

Fingerprint

Hemodiafiltration
Serum
Ultrafiltration
Electrolytes
Chronic Kidney Failure
Dialysis
Erythrocytes
Heart Rate
Blood Pressure

Keywords

  • Acetate Free Biofiltration
  • Arrhythmia
  • End-stage renal disease
  • QTc dispersion
  • QTc interval

ASJC Scopus subject areas

  • Nephrology

Cite this

Floccari, F., Aloisi, E., Nostro, L., Caccamo, C., Crisafulli, A., Barillà, A., ... Buemi, M. (2004). QTc interval and QTc dispersion during haemodiafiltration. Nephrology, 9(6), 335-340. https://doi.org/10.1111/j.1440-1797.2004.00333.x

QTc interval and QTc dispersion during haemodiafiltration. / Floccari, Fulvio; Aloisi, Emanuele; Nostro, Lorena; Caccamo, Chiara; Crisafulli, Alessandra; Barillà, Antonio; Aloisi, Carmela; Romeo, Adolfo; Corica, Francesco; Ientile, Riccardo; Frisina, Nicola; Buemi, Michele.

In: Nephrology, Vol. 9, No. 6, 12.2004, p. 335-340.

Research output: Contribution to journalArticle

Floccari, F, Aloisi, E, Nostro, L, Caccamo, C, Crisafulli, A, Barillà, A, Aloisi, C, Romeo, A, Corica, F, Ientile, R, Frisina, N & Buemi, M 2004, 'QTc interval and QTc dispersion during haemodiafiltration', Nephrology, vol. 9, no. 6, pp. 335-340. https://doi.org/10.1111/j.1440-1797.2004.00333.x
Floccari F, Aloisi E, Nostro L, Caccamo C, Crisafulli A, Barillà A et al. QTc interval and QTc dispersion during haemodiafiltration. Nephrology. 2004 Dec;9(6):335-340. https://doi.org/10.1111/j.1440-1797.2004.00333.x
Floccari, Fulvio ; Aloisi, Emanuele ; Nostro, Lorena ; Caccamo, Chiara ; Crisafulli, Alessandra ; Barillà, Antonio ; Aloisi, Carmela ; Romeo, Adolfo ; Corica, Francesco ; Ientile, Riccardo ; Frisina, Nicola ; Buemi, Michele. / QTc interval and QTc dispersion during haemodiafiltration. In: Nephrology. 2004 ; Vol. 9, No. 6. pp. 335-340.
@article{13651f272b7c4f4bb838b9ff564ba69a,
title = "QTc interval and QTc dispersion during haemodiafiltration",
abstract = "Background and Aim: Our aim was to evaluate QTc interval and QTc dispersion in 27 end-stage renal disease (ESRD) patients undergoing Acetate Free Biofiltration (AFB) in order to ascertain any correlations between the electrrocardiographic (ECG) parameters, serum Na+, K+, Ca++, Mg++ and intraerythrocytic Mg++ (Mg++e) concentrations. All measures were made at to (session beginning), t1 (first hour), t2 (second hour), t3 (third hour), and t4 (session end). Results: Blood pressure, heart rate, bodyweight and total ultrafiltration in the three dialysis sessions were constant. A significant progressive increase occurred in serum Ca++ during the sessions, while there was a significant diminution in serum K+. The pattern for Mg++ concentrations in serum and erythrocytes differed: in serum it decreased, whereas Mg++e increased. At t4, the QTc interval was reduced to a significant extent with respect to the baseline value. QTc dispersion significantly increased at t1 without there being significant variations at other times with respect to t0. At t2, t3 and t4, values promptly returned to baseline levels. QTc had a negative correlation with serum Ca++ levels at t4. In contrast, an inverse correlation was found between QTc dispersion and serum K+ at t1. No other correlations could be found between any other electrolytes, QTc interval or QTc dispersion. Conclusion: In conclusion, the decrease observed in the QTc interval at the end of an AFB session was inversely related to serum Ca++ concentrations. Moreover, an increase in QTc dispersion occurred during the first hour of the session, and was negatively correlated with serum K+.",
keywords = "Acetate Free Biofiltration, Arrhythmia, End-stage renal disease, QTc dispersion, QTc interval",
author = "Fulvio Floccari and Emanuele Aloisi and Lorena Nostro and Chiara Caccamo and Alessandra Crisafulli and Antonio Barill{\`a} and Carmela Aloisi and Adolfo Romeo and Francesco Corica and Riccardo Ientile and Nicola Frisina and Michele Buemi",
year = "2004",
month = "12",
doi = "10.1111/j.1440-1797.2004.00333.x",
language = "English",
volume = "9",
pages = "335--340",
journal = "Nephrology",
issn = "1320-5358",
publisher = "Wiley-Blackwell",
number = "6",

}

TY - JOUR

T1 - QTc interval and QTc dispersion during haemodiafiltration

AU - Floccari, Fulvio

AU - Aloisi, Emanuele

AU - Nostro, Lorena

AU - Caccamo, Chiara

AU - Crisafulli, Alessandra

AU - Barillà, Antonio

AU - Aloisi, Carmela

AU - Romeo, Adolfo

AU - Corica, Francesco

AU - Ientile, Riccardo

AU - Frisina, Nicola

AU - Buemi, Michele

PY - 2004/12

Y1 - 2004/12

N2 - Background and Aim: Our aim was to evaluate QTc interval and QTc dispersion in 27 end-stage renal disease (ESRD) patients undergoing Acetate Free Biofiltration (AFB) in order to ascertain any correlations between the electrrocardiographic (ECG) parameters, serum Na+, K+, Ca++, Mg++ and intraerythrocytic Mg++ (Mg++e) concentrations. All measures were made at to (session beginning), t1 (first hour), t2 (second hour), t3 (third hour), and t4 (session end). Results: Blood pressure, heart rate, bodyweight and total ultrafiltration in the three dialysis sessions were constant. A significant progressive increase occurred in serum Ca++ during the sessions, while there was a significant diminution in serum K+. The pattern for Mg++ concentrations in serum and erythrocytes differed: in serum it decreased, whereas Mg++e increased. At t4, the QTc interval was reduced to a significant extent with respect to the baseline value. QTc dispersion significantly increased at t1 without there being significant variations at other times with respect to t0. At t2, t3 and t4, values promptly returned to baseline levels. QTc had a negative correlation with serum Ca++ levels at t4. In contrast, an inverse correlation was found between QTc dispersion and serum K+ at t1. No other correlations could be found between any other electrolytes, QTc interval or QTc dispersion. Conclusion: In conclusion, the decrease observed in the QTc interval at the end of an AFB session was inversely related to serum Ca++ concentrations. Moreover, an increase in QTc dispersion occurred during the first hour of the session, and was negatively correlated with serum K+.

AB - Background and Aim: Our aim was to evaluate QTc interval and QTc dispersion in 27 end-stage renal disease (ESRD) patients undergoing Acetate Free Biofiltration (AFB) in order to ascertain any correlations between the electrrocardiographic (ECG) parameters, serum Na+, K+, Ca++, Mg++ and intraerythrocytic Mg++ (Mg++e) concentrations. All measures were made at to (session beginning), t1 (first hour), t2 (second hour), t3 (third hour), and t4 (session end). Results: Blood pressure, heart rate, bodyweight and total ultrafiltration in the three dialysis sessions were constant. A significant progressive increase occurred in serum Ca++ during the sessions, while there was a significant diminution in serum K+. The pattern for Mg++ concentrations in serum and erythrocytes differed: in serum it decreased, whereas Mg++e increased. At t4, the QTc interval was reduced to a significant extent with respect to the baseline value. QTc dispersion significantly increased at t1 without there being significant variations at other times with respect to t0. At t2, t3 and t4, values promptly returned to baseline levels. QTc had a negative correlation with serum Ca++ levels at t4. In contrast, an inverse correlation was found between QTc dispersion and serum K+ at t1. No other correlations could be found between any other electrolytes, QTc interval or QTc dispersion. Conclusion: In conclusion, the decrease observed in the QTc interval at the end of an AFB session was inversely related to serum Ca++ concentrations. Moreover, an increase in QTc dispersion occurred during the first hour of the session, and was negatively correlated with serum K+.

KW - Acetate Free Biofiltration

KW - Arrhythmia

KW - End-stage renal disease

KW - QTc dispersion

KW - QTc interval

UR - http://www.scopus.com/inward/record.url?scp=19944425936&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=19944425936&partnerID=8YFLogxK

U2 - 10.1111/j.1440-1797.2004.00333.x

DO - 10.1111/j.1440-1797.2004.00333.x

M3 - Article

VL - 9

SP - 335

EP - 340

JO - Nephrology

JF - Nephrology

SN - 1320-5358

IS - 6

ER -