Abstract
Background and Aim: Our aim was to evaluate QTc interval and QTc dispersion in 27 end-stage renal disease (ESRD) patients undergoing Acetate Free Biofiltration (AFB) in order to ascertain any correlations between the electrrocardiographic (ECG) parameters, serum Na+, K+, Ca++, Mg++ and intraerythrocytic Mg++ (Mg++e) concentrations. All measures were made at to (session beginning), t1 (first hour), t2 (second hour), t3 (third hour), and t4 (session end). Results: Blood pressure, heart rate, bodyweight and total ultrafiltration in the three dialysis sessions were constant. A significant progressive increase occurred in serum Ca++ during the sessions, while there was a significant diminution in serum K+. The pattern for Mg++ concentrations in serum and erythrocytes differed: in serum it decreased, whereas Mg++e increased. At t4, the QTc interval was reduced to a significant extent with respect to the baseline value. QTc dispersion significantly increased at t1 without there being significant variations at other times with respect to t0. At t2, t3 and t4, values promptly returned to baseline levels. QTc had a negative correlation with serum Ca++ levels at t4. In contrast, an inverse correlation was found between QTc dispersion and serum K+ at t1. No other correlations could be found between any other electrolytes, QTc interval or QTc dispersion. Conclusion: In conclusion, the decrease observed in the QTc interval at the end of an AFB session was inversely related to serum Ca++ concentrations. Moreover, an increase in QTc dispersion occurred during the first hour of the session, and was negatively correlated with serum K+.
| Original language | English |
|---|---|
| Pages (from-to) | 335-340 |
| Number of pages | 6 |
| Journal | Nephrology |
| Volume | 9 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Dec 2004 |
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Keywords
- Acetate Free Biofiltration
- Arrhythmia
- End-stage renal disease
- QTc dispersion
- QTc interval
ASJC Scopus subject areas
- Nephrology
Cite this
QTc interval and QTc dispersion during haemodiafiltration. / Floccari, Fulvio; Aloisi, Emanuele; Nostro, Lorena; Caccamo, Chiara; Crisafulli, Alessandra; Barillà, Antonio; Aloisi, Carmela; Romeo, Adolfo; Corica, Francesco; Ientile, Riccardo; Frisina, Nicola; Buemi, Michele.
In: Nephrology, Vol. 9, No. 6, 12.2004, p. 335-340.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - QTc interval and QTc dispersion during haemodiafiltration
AU - Floccari, Fulvio
AU - Aloisi, Emanuele
AU - Nostro, Lorena
AU - Caccamo, Chiara
AU - Crisafulli, Alessandra
AU - Barillà, Antonio
AU - Aloisi, Carmela
AU - Romeo, Adolfo
AU - Corica, Francesco
AU - Ientile, Riccardo
AU - Frisina, Nicola
AU - Buemi, Michele
PY - 2004/12
Y1 - 2004/12
N2 - Background and Aim: Our aim was to evaluate QTc interval and QTc dispersion in 27 end-stage renal disease (ESRD) patients undergoing Acetate Free Biofiltration (AFB) in order to ascertain any correlations between the electrrocardiographic (ECG) parameters, serum Na+, K+, Ca++, Mg++ and intraerythrocytic Mg++ (Mg++e) concentrations. All measures were made at to (session beginning), t1 (first hour), t2 (second hour), t3 (third hour), and t4 (session end). Results: Blood pressure, heart rate, bodyweight and total ultrafiltration in the three dialysis sessions were constant. A significant progressive increase occurred in serum Ca++ during the sessions, while there was a significant diminution in serum K+. The pattern for Mg++ concentrations in serum and erythrocytes differed: in serum it decreased, whereas Mg++e increased. At t4, the QTc interval was reduced to a significant extent with respect to the baseline value. QTc dispersion significantly increased at t1 without there being significant variations at other times with respect to t0. At t2, t3 and t4, values promptly returned to baseline levels. QTc had a negative correlation with serum Ca++ levels at t4. In contrast, an inverse correlation was found between QTc dispersion and serum K+ at t1. No other correlations could be found between any other electrolytes, QTc interval or QTc dispersion. Conclusion: In conclusion, the decrease observed in the QTc interval at the end of an AFB session was inversely related to serum Ca++ concentrations. Moreover, an increase in QTc dispersion occurred during the first hour of the session, and was negatively correlated with serum K+.
AB - Background and Aim: Our aim was to evaluate QTc interval and QTc dispersion in 27 end-stage renal disease (ESRD) patients undergoing Acetate Free Biofiltration (AFB) in order to ascertain any correlations between the electrrocardiographic (ECG) parameters, serum Na+, K+, Ca++, Mg++ and intraerythrocytic Mg++ (Mg++e) concentrations. All measures were made at to (session beginning), t1 (first hour), t2 (second hour), t3 (third hour), and t4 (session end). Results: Blood pressure, heart rate, bodyweight and total ultrafiltration in the three dialysis sessions were constant. A significant progressive increase occurred in serum Ca++ during the sessions, while there was a significant diminution in serum K+. The pattern for Mg++ concentrations in serum and erythrocytes differed: in serum it decreased, whereas Mg++e increased. At t4, the QTc interval was reduced to a significant extent with respect to the baseline value. QTc dispersion significantly increased at t1 without there being significant variations at other times with respect to t0. At t2, t3 and t4, values promptly returned to baseline levels. QTc had a negative correlation with serum Ca++ levels at t4. In contrast, an inverse correlation was found between QTc dispersion and serum K+ at t1. No other correlations could be found between any other electrolytes, QTc interval or QTc dispersion. Conclusion: In conclusion, the decrease observed in the QTc interval at the end of an AFB session was inversely related to serum Ca++ concentrations. Moreover, an increase in QTc dispersion occurred during the first hour of the session, and was negatively correlated with serum K+.
KW - Acetate Free Biofiltration
KW - Arrhythmia
KW - End-stage renal disease
KW - QTc dispersion
KW - QTc interval
UR - http://www.scopus.com/inward/record.url?scp=19944425936&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=19944425936&partnerID=8YFLogxK
U2 - 10.1111/j.1440-1797.2004.00333.x
DO - 10.1111/j.1440-1797.2004.00333.x
M3 - Article
VL - 9
SP - 335
EP - 340
JO - Nephrology
JF - Nephrology
SN - 1320-5358
IS - 6
ER -