Abstract
Background: Treatment of HIV-infected patients with interleukin-2 (IL-2) produces significant increases in CD4 T cell counts; however an associated qualitative improvement in cells function has yet to be conclusively demonstrated. By measuring mycobacterial killing activity, we evaluated IL-2-mediated functional immune enhancement ex vivo in immunological nonresponders (INRs). Methods and Findings: PBMC from 12 immunological non-responders (INRs) (CD4+
Original language | English |
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Article number | e14119 |
Journal | PLoS One |
Volume | 5 |
Issue number | 11 |
DOIs | |
Publication status | Published - 2010 |
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Medicine(all)