Quality analysis of population-based information on cancer stage at diagnosis across Europe, with presentation of stage-specific cancer survival estimates: A EUROCARE-5 study

P. Minicozzi, K. Innos, M.-J. Sánchez, A. Trama, P.M. Walsh, R. Marcos-Gragera, N. Dimitrova, L. Botta, O. Visser, S. Rossi, A. Tavilla, EUROCARE-5 Working Group, R. De Angelis, M. Caldora, S. Francisci, A. Knijn, S. Mallone, D. Pierannunzio, M. Santaquilani, Eugenio Carrani & 1 others P. Roazzi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background Cancer registries (CRs) are fundamental for estimating cancer burden, evaluating screening and monitoring health service performance. Stage at diagnosis—an essential information item collected by CRs—has been made available, for the first time, by CRs participating in EUROCARE-5. We analysed the quality of this information and estimated stage-specific survival across Europe for CRs with good data quality. Data and methods Sixty-two CRs sent stage (as TNM, condensed TNM or extent of disease) for 15 cancers diagnosed in 2000–2007. We assessed the quality, partly by comparing stage according to the three systems. We also developed procedures to reconstruct stage (categories: local, regional, metastatic and unknown) using information from all three systems, thus minimising the amount of missing information. Results Moderate-to-excellent stage concordance was found for practically all 24 CRs, for which it was possible to compare at least two staging systems. However, since stage was often incorrectly assigned, and information on the presence/absence of metastases was often lacking, data on only 7/15 cancers from 34/62 CRs (15 countries) were of sufficient quality for further analysis. Cases diagnosed ≥70 years had more advanced (or lacking) stage– and worse stage-specific survival than those
Original languageEnglish
Pages (from-to)335-353
Number of pages19
JournalEuropean Journal of Cancer
Volume84
DOIs
Publication statusPublished - 2017

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Population
Neoplasms
Health Services
Neoplasm Metastasis

Keywords

  • Cancer registries
  • Data quality
  • Stage at diagnosis
  • Survival
  • Article
  • bladder cancer
  • breast cancer
  • cancer diagnosis
  • cancer localization
  • cancer patient
  • cancer registry
  • cancer staging
  • cancer survival
  • colon cancer
  • comparative study
  • controlled study
  • human
  • kidney cancer
  • lung cancer
  • major clinical study
  • malignant neoplasm
  • melanoma
  • ovary cancer
  • priority journal
  • prostate cancer
  • rectum cancer
  • stomach cancer
  • testis cancer
  • thyroid cancer
  • uterine cervix cancer
  • uterus cancer
  • vagina cancer
  • clinical trial
  • epidemiology
  • Europe
  • female
  • male
  • measurement accuracy
  • metastasis
  • mortality
  • multicenter study
  • Neoplasms
  • pathology
  • predictive value
  • register
  • reproducibility
  • survival analysis
  • Data Accuracy
  • Female
  • Humans
  • Male
  • Neoplasm Metastasis
  • Neoplasm Staging
  • Predictive Value of Tests
  • Registries
  • Reproducibility of Results
  • Survival Analysis

Cite this

Quality analysis of population-based information on cancer stage at diagnosis across Europe, with presentation of stage-specific cancer survival estimates: A EUROCARE-5 study. / Minicozzi, P.; Innos, K.; Sánchez, M.-J.; Trama, A.; Walsh, P.M.; Marcos-Gragera, R.; Dimitrova, N.; Botta, L.; Visser, O.; Rossi, S.; Tavilla, A.; Group, EUROCARE-5 Working; De Angelis, R.; Caldora, M.; Francisci, S.; Knijn, A.; Mallone, S.; Pierannunzio, D.; Santaquilani, M.; Carrani, Eugenio; Roazzi, P.

In: European Journal of Cancer, Vol. 84, 2017, p. 335-353.

Research output: Contribution to journalArticle

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title = "Quality analysis of population-based information on cancer stage at diagnosis across Europe, with presentation of stage-specific cancer survival estimates: A EUROCARE-5 study",
abstract = "Background Cancer registries (CRs) are fundamental for estimating cancer burden, evaluating screening and monitoring health service performance. Stage at diagnosis—an essential information item collected by CRs—has been made available, for the first time, by CRs participating in EUROCARE-5. We analysed the quality of this information and estimated stage-specific survival across Europe for CRs with good data quality. Data and methods Sixty-two CRs sent stage (as TNM, condensed TNM or extent of disease) for 15 cancers diagnosed in 2000–2007. We assessed the quality, partly by comparing stage according to the three systems. We also developed procedures to reconstruct stage (categories: local, regional, metastatic and unknown) using information from all three systems, thus minimising the amount of missing information. Results Moderate-to-excellent stage concordance was found for practically all 24 CRs, for which it was possible to compare at least two staging systems. However, since stage was often incorrectly assigned, and information on the presence/absence of metastases was often lacking, data on only 7/15 cancers from 34/62 CRs (15 countries) were of sufficient quality for further analysis. Cases diagnosed ≥70 years had more advanced (or lacking) stage– and worse stage-specific survival than those",
keywords = "Cancer registries, Data quality, Stage at diagnosis, Survival, Article, bladder cancer, breast cancer, cancer diagnosis, cancer localization, cancer patient, cancer registry, cancer staging, cancer survival, colon cancer, comparative study, controlled study, human, kidney cancer, lung cancer, major clinical study, malignant neoplasm, melanoma, ovary cancer, priority journal, prostate cancer, rectum cancer, stomach cancer, testis cancer, thyroid cancer, uterine cervix cancer, uterus cancer, vagina cancer, clinical trial, epidemiology, Europe, female, male, measurement accuracy, metastasis, mortality, multicenter study, Neoplasms, pathology, predictive value, register, reproducibility, survival analysis, Data Accuracy, Female, Humans, Male, Neoplasm Metastasis, Neoplasm Staging, Predictive Value of Tests, Registries, Reproducibility of Results, Survival Analysis",
author = "P. Minicozzi and K. Innos and M.-J. S{\'a}nchez and A. Trama and P.M. Walsh and R. Marcos-Gragera and N. Dimitrova and L. Botta and O. Visser and S. Rossi and A. Tavilla and Group, {EUROCARE-5 Working} and {De Angelis}, R. and M. Caldora and S. Francisci and A. Knijn and S. Mallone and D. Pierannunzio and M. Santaquilani and Eugenio Carrani and P. Roazzi",
note = "Cited By :2 Export Date: 10 April 2018 CODEN: EJCAE Correspondence Address: Minicozzi, P.; Analytical Epidemiology and Health Impact Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, Italy; email: pamela.minicozzi@istitutotumori.mi.it Funding details: 20102202, Bone and Joint Canada Funding details: Compagnia di San Paolo Funding details: European Commission Funding details: RF-2009-1529710, Ministry of Health Funding details: Fondazione Cariplo Funding details: European League Against Rheumatism Funding details: Ministry of Health Funding text: The Compagnia di San Paolo, the Fondazione Cariplo Italy, the Italian Ministry of Health (Ricerca Finalizzata 2009, RF-2009-1529710 ) and the European Commission (European Action Against Cancer, EPAAC, Joint Action No. 20102202 ). References: Antilla, A., L{\"o}nnberg, S., Ponti, A., Suonio, E., Villain, P., Coebergh, J.W., Towards better implementation of cancer screening in Europe improved monitoring and evaluation and greater engagement of cancer registries (2015) Eur J Cancer, 51, pp. 241-251; Coebergh, J.W., van der Hurk, C., Rosso, S., Comber, H., Storm, H., Zanetti, R., EUROCOURSE lessons learned from and for population-based cancer registries in Europe and their programme owners: improving performance by research programming for public health and clinical evaluation (2015) Eur J Cancer, 51, pp. 997-1017; Rossi, S., Baili, P., Capocaccia, R., Caldora, M., Carrani, E., Minicozzi, P., The EUROCARE-5 study on cancer survival in Europe 1999–2007: database, quality checks and statistical analysis methods (2015) Eur J Cancer, 51, pp. 2104-2119; McHugh, M.L., Interrater reliability: the kappa statistic (2012) Biochem Med, 22, pp. 276-282; Siesling, S., Louwman, W.J., Kwast, A., van den Hurk, C., O'Callaghan, M., Rosso, S., Uses of CRs for public health and clinical research in Europe: results of the European Network of CRs survey among the 161 population-based CRs during 2010–2012 (2015) Eur J Cancer, 51, pp. 1039-1049; Breugom, A.J., Bastiaannet, E., Boelens, P.G., Iversen, L.H., Martling, A., Johansson, R., Adjuvant chemotherapy and relative survival of patients with stage II colon cancer – a EURECCA international comparison between The Netherlands, Denmark, Sweden, England, Ireland, Belgium, and Lithuania (2016) Eur J Cancer, 63, pp. 110-117; Walters, S., Maringe, C., Coleman, M.P., Peake, M.D., Butler, J., Young, N., Lung cancer survival and stage at diagnosis in Australia, Canada, Denmark, Norway, Sweden and the UK: a population-based study, 2004–2007 (2013) Thorax, 68, pp. 551-564; Visser, O., van Leeuwen, F.E., Stage-specific survival of epithelial cancers in North-Holland/Flevoland, The Netherlands (2005) Eur J Cancer, 41, pp. 2321-2330; Eberle, A., Jansen, L., Castro, F., Krilaviciute, A., Luttmann, S., Emrich, K., Lung cancer survival in Germany: a population-based analysis of 132,612 lung cancer patients (2015) Lung Cancer, 90, pp. 528-533; Ojamaa, K., Veerus, P., Baburin, A., Everaus, H., Innos, K., Time trends in ovarian cancer survival in Estonia by age and stage (2017) Int J Gynecol Cancer, 27, pp. 44-49; Forsea, A.M., Cancer registries in Europe-going forward is the only option (2016) Ecancermedicalscience, 10, p. 641; Dudek-Godeau, D., Kieszkowska-Grudny, A., Kwiatkowska, K., Bogusz, J., Wysocki, M.J., Bielska-Lasota, M., Analysis of changes in cancer health care system in Poland since the socio-economic transformation in 1989 (2016) Rocz Panstw Zakl Hig, 67, pp. 445-454; Sobin, L.H., Compton, C.C., TNM seventh edition: what's new, what's changed: communication from the International Union Against Cancer and the American Joint Committee on Cancer (2010) Cancer, 15 (116), pp. 5336-5339; Walters, S., Maringe, C., Butler, J., Brierley, J.D., Rachet, B., Coleman, M.P., Comparability of stage data in CRs in six countries: lessons from the International Cancer Benchmarking Partnership (2013) Int J Cancer, 132, pp. 676-685; Benitez-Majano, S., Fowler, H., Maringe, C., Di Girolamo, C., Rachet, B., Deriving stage at diagnosis from multiple population-based sources: colorectal and lung cancer in England (2016) Br J Cancer, 115, pp. 391-400; Eisemann, N., Waldmann, A., Katalinic, A., Imputation of missing values of tumour stage in population-based cancer registration (2011) BMC Med Res Methodol, 11, p. 129; Sant, M., Allemani, C., Berrino, F., Coleman, M.P., Aareleid, T., Chaplain, G., Breast carcinoma survival in Europe and the United States: a population-based study (2004) Cancer, 100, pp. 715-722; Ciccolallo, L., Capocaccia, R., Coleman, M.P., Berrino, F., Coebergh, J.W., Damhuis, R.A., Survival differences between European and US patients with colorectal cancer: role of stage at diagnosis and surgery (2005) Gut, 54, pp. 268-273;",
year = "2017",
doi = "10.1016/j.ejca.2017.07.015",
language = "English",
volume = "84",
pages = "335--353",
journal = "European Journal of Cancer",
issn = "0959-8049",
publisher = "Elsevier Ltd",

}

TY - JOUR

T1 - Quality analysis of population-based information on cancer stage at diagnosis across Europe, with presentation of stage-specific cancer survival estimates: A EUROCARE-5 study

AU - Minicozzi, P.

AU - Innos, K.

AU - Sánchez, M.-J.

AU - Trama, A.

AU - Walsh, P.M.

AU - Marcos-Gragera, R.

AU - Dimitrova, N.

AU - Botta, L.

AU - Visser, O.

AU - Rossi, S.

AU - Tavilla, A.

AU - Group, EUROCARE-5 Working

AU - De Angelis, R.

AU - Caldora, M.

AU - Francisci, S.

AU - Knijn, A.

AU - Mallone, S.

AU - Pierannunzio, D.

AU - Santaquilani, M.

AU - Carrani, Eugenio

AU - Roazzi, P.

N1 - Cited By :2 Export Date: 10 April 2018 CODEN: EJCAE Correspondence Address: Minicozzi, P.; Analytical Epidemiology and Health Impact Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, Italy; email: pamela.minicozzi@istitutotumori.mi.it Funding details: 20102202, Bone and Joint Canada Funding details: Compagnia di San Paolo Funding details: European Commission Funding details: RF-2009-1529710, Ministry of Health Funding details: Fondazione Cariplo Funding details: European League Against Rheumatism Funding details: Ministry of Health Funding text: The Compagnia di San Paolo, the Fondazione Cariplo Italy, the Italian Ministry of Health (Ricerca Finalizzata 2009, RF-2009-1529710 ) and the European Commission (European Action Against Cancer, EPAAC, Joint Action No. 20102202 ). References: Antilla, A., Lönnberg, S., Ponti, A., Suonio, E., Villain, P., Coebergh, J.W., Towards better implementation of cancer screening in Europe improved monitoring and evaluation and greater engagement of cancer registries (2015) Eur J Cancer, 51, pp. 241-251; Coebergh, J.W., van der Hurk, C., Rosso, S., Comber, H., Storm, H., Zanetti, R., EUROCOURSE lessons learned from and for population-based cancer registries in Europe and their programme owners: improving performance by research programming for public health and clinical evaluation (2015) Eur J Cancer, 51, pp. 997-1017; Rossi, S., Baili, P., Capocaccia, R., Caldora, M., Carrani, E., Minicozzi, P., The EUROCARE-5 study on cancer survival in Europe 1999–2007: database, quality checks and statistical analysis methods (2015) Eur J Cancer, 51, pp. 2104-2119; McHugh, M.L., Interrater reliability: the kappa statistic (2012) Biochem Med, 22, pp. 276-282; Siesling, S., Louwman, W.J., Kwast, A., van den Hurk, C., O'Callaghan, M., Rosso, S., Uses of CRs for public health and clinical research in Europe: results of the European Network of CRs survey among the 161 population-based CRs during 2010–2012 (2015) Eur J Cancer, 51, pp. 1039-1049; Breugom, A.J., Bastiaannet, E., Boelens, P.G., Iversen, L.H., Martling, A., Johansson, R., Adjuvant chemotherapy and relative survival of patients with stage II colon cancer – a EURECCA international comparison between The Netherlands, Denmark, Sweden, England, Ireland, Belgium, and Lithuania (2016) Eur J Cancer, 63, pp. 110-117; Walters, S., Maringe, C., Coleman, M.P., Peake, M.D., Butler, J., Young, N., Lung cancer survival and stage at diagnosis in Australia, Canada, Denmark, Norway, Sweden and the UK: a population-based study, 2004–2007 (2013) Thorax, 68, pp. 551-564; Visser, O., van Leeuwen, F.E., Stage-specific survival of epithelial cancers in North-Holland/Flevoland, The Netherlands (2005) Eur J Cancer, 41, pp. 2321-2330; Eberle, A., Jansen, L., Castro, F., Krilaviciute, A., Luttmann, S., Emrich, K., Lung cancer survival in Germany: a population-based analysis of 132,612 lung cancer patients (2015) Lung Cancer, 90, pp. 528-533; Ojamaa, K., Veerus, P., Baburin, A., Everaus, H., Innos, K., Time trends in ovarian cancer survival in Estonia by age and stage (2017) Int J Gynecol Cancer, 27, pp. 44-49; Forsea, A.M., Cancer registries in Europe-going forward is the only option (2016) Ecancermedicalscience, 10, p. 641; Dudek-Godeau, D., Kieszkowska-Grudny, A., Kwiatkowska, K., Bogusz, J., Wysocki, M.J., Bielska-Lasota, M., Analysis of changes in cancer health care system in Poland since the socio-economic transformation in 1989 (2016) Rocz Panstw Zakl Hig, 67, pp. 445-454; Sobin, L.H., Compton, C.C., TNM seventh edition: what's new, what's changed: communication from the International Union Against Cancer and the American Joint Committee on Cancer (2010) Cancer, 15 (116), pp. 5336-5339; Walters, S., Maringe, C., Butler, J., Brierley, J.D., Rachet, B., Coleman, M.P., Comparability of stage data in CRs in six countries: lessons from the International Cancer Benchmarking Partnership (2013) Int J Cancer, 132, pp. 676-685; Benitez-Majano, S., Fowler, H., Maringe, C., Di Girolamo, C., Rachet, B., Deriving stage at diagnosis from multiple population-based sources: colorectal and lung cancer in England (2016) Br J Cancer, 115, pp. 391-400; Eisemann, N., Waldmann, A., Katalinic, A., Imputation of missing values of tumour stage in population-based cancer registration (2011) BMC Med Res Methodol, 11, p. 129; Sant, M., Allemani, C., Berrino, F., Coleman, M.P., Aareleid, T., Chaplain, G., Breast carcinoma survival in Europe and the United States: a population-based study (2004) Cancer, 100, pp. 715-722; Ciccolallo, L., Capocaccia, R., Coleman, M.P., Berrino, F., Coebergh, J.W., Damhuis, R.A., Survival differences between European and US patients with colorectal cancer: role of stage at diagnosis and surgery (2005) Gut, 54, pp. 268-273;

PY - 2017

Y1 - 2017

N2 - Background Cancer registries (CRs) are fundamental for estimating cancer burden, evaluating screening and monitoring health service performance. Stage at diagnosis—an essential information item collected by CRs—has been made available, for the first time, by CRs participating in EUROCARE-5. We analysed the quality of this information and estimated stage-specific survival across Europe for CRs with good data quality. Data and methods Sixty-two CRs sent stage (as TNM, condensed TNM or extent of disease) for 15 cancers diagnosed in 2000–2007. We assessed the quality, partly by comparing stage according to the three systems. We also developed procedures to reconstruct stage (categories: local, regional, metastatic and unknown) using information from all three systems, thus minimising the amount of missing information. Results Moderate-to-excellent stage concordance was found for practically all 24 CRs, for which it was possible to compare at least two staging systems. However, since stage was often incorrectly assigned, and information on the presence/absence of metastases was often lacking, data on only 7/15 cancers from 34/62 CRs (15 countries) were of sufficient quality for further analysis. Cases diagnosed ≥70 years had more advanced (or lacking) stage– and worse stage-specific survival than those

AB - Background Cancer registries (CRs) are fundamental for estimating cancer burden, evaluating screening and monitoring health service performance. Stage at diagnosis—an essential information item collected by CRs—has been made available, for the first time, by CRs participating in EUROCARE-5. We analysed the quality of this information and estimated stage-specific survival across Europe for CRs with good data quality. Data and methods Sixty-two CRs sent stage (as TNM, condensed TNM or extent of disease) for 15 cancers diagnosed in 2000–2007. We assessed the quality, partly by comparing stage according to the three systems. We also developed procedures to reconstruct stage (categories: local, regional, metastatic and unknown) using information from all three systems, thus minimising the amount of missing information. Results Moderate-to-excellent stage concordance was found for practically all 24 CRs, for which it was possible to compare at least two staging systems. However, since stage was often incorrectly assigned, and information on the presence/absence of metastases was often lacking, data on only 7/15 cancers from 34/62 CRs (15 countries) were of sufficient quality for further analysis. Cases diagnosed ≥70 years had more advanced (or lacking) stage– and worse stage-specific survival than those

KW - Cancer registries

KW - Data quality

KW - Stage at diagnosis

KW - Survival

KW - Article

KW - bladder cancer

KW - breast cancer

KW - cancer diagnosis

KW - cancer localization

KW - cancer patient

KW - cancer registry

KW - cancer staging

KW - cancer survival

KW - colon cancer

KW - comparative study

KW - controlled study

KW - human

KW - kidney cancer

KW - lung cancer

KW - major clinical study

KW - malignant neoplasm

KW - melanoma

KW - ovary cancer

KW - priority journal

KW - prostate cancer

KW - rectum cancer

KW - stomach cancer

KW - testis cancer

KW - thyroid cancer

KW - uterine cervix cancer

KW - uterus cancer

KW - vagina cancer

KW - clinical trial

KW - epidemiology

KW - Europe

KW - female

KW - male

KW - measurement accuracy

KW - metastasis

KW - mortality

KW - multicenter study

KW - Neoplasms

KW - pathology

KW - predictive value

KW - register

KW - reproducibility

KW - survival analysis

KW - Data Accuracy

KW - Female

KW - Humans

KW - Male

KW - Neoplasm Metastasis

KW - Neoplasm Staging

KW - Predictive Value of Tests

KW - Registries

KW - Reproducibility of Results

KW - Survival Analysis

U2 - 10.1016/j.ejca.2017.07.015

DO - 10.1016/j.ejca.2017.07.015

M3 - Article

VL - 84

SP - 335

EP - 353

JO - European Journal of Cancer

JF - European Journal of Cancer

SN - 0959-8049

ER -