Quality assurance of platelet concentrates used in routine practice

Research output: Contribution to journalArticle

Abstract

Quality assurance of platelet concentrates should include regular determinations on sampled units of platelet concentrate volume, platelet count, pH value and an indicator of maintenance of platelet discoid shape. In regard to the latter, recent investigations suggest that the visual assessment of platelet swirling may provide meaningful and reproducible information with limited staff training and efforts. Other laboratory assays provide useful data that may prove beneficial particulary when new procedures and products are examined. In addition to laboratory tests, it is of utmost importance to regularly monitor the effectiveness of platelet support therapy at clinical level. This can be done using a number of indicators including the proportion of patients who show febrile, allergic and septic reactions, who become and remain refractory to random-donor platelet support, who develop and/or die of hemorrhage not prevented or corrected by platelet support.

Original languageEnglish
Pages (from-to)95-97
Number of pages3
JournalInternational Journal of Artificial Organs
Volume21
Issue numberSUPPL. 6
Publication statusPublished - 1998

Fingerprint

Platelets
Quality assurance
Blood Platelets
Feline Panleukopenia
Platelet Count
Refractory materials
Hypersensitivity
Assays
Maintenance
Tissue Donors
Hemorrhage

Keywords

  • Platelet transfusion
  • Quality assurance

ASJC Scopus subject areas

  • Biophysics

Cite this

Quality assurance of platelet concentrates used in routine practice. / Rebulla, P.

In: International Journal of Artificial Organs, Vol. 21, No. SUPPL. 6, 1998, p. 95-97.

Research output: Contribution to journalArticle

@article{93b5eca590314196b50650e090efd61a,
title = "Quality assurance of platelet concentrates used in routine practice",
abstract = "Quality assurance of platelet concentrates should include regular determinations on sampled units of platelet concentrate volume, platelet count, pH value and an indicator of maintenance of platelet discoid shape. In regard to the latter, recent investigations suggest that the visual assessment of platelet swirling may provide meaningful and reproducible information with limited staff training and efforts. Other laboratory assays provide useful data that may prove beneficial particulary when new procedures and products are examined. In addition to laboratory tests, it is of utmost importance to regularly monitor the effectiveness of platelet support therapy at clinical level. This can be done using a number of indicators including the proportion of patients who show febrile, allergic and septic reactions, who become and remain refractory to random-donor platelet support, who develop and/or die of hemorrhage not prevented or corrected by platelet support.",
keywords = "Platelet transfusion, Quality assurance",
author = "P. Rebulla",
year = "1998",
language = "English",
volume = "21",
pages = "95--97",
journal = "International Journal of Artificial Organs",
issn = "0391-3988",
publisher = "Wichtig Publishing",
number = "SUPPL. 6",

}

TY - JOUR

T1 - Quality assurance of platelet concentrates used in routine practice

AU - Rebulla, P.

PY - 1998

Y1 - 1998

N2 - Quality assurance of platelet concentrates should include regular determinations on sampled units of platelet concentrate volume, platelet count, pH value and an indicator of maintenance of platelet discoid shape. In regard to the latter, recent investigations suggest that the visual assessment of platelet swirling may provide meaningful and reproducible information with limited staff training and efforts. Other laboratory assays provide useful data that may prove beneficial particulary when new procedures and products are examined. In addition to laboratory tests, it is of utmost importance to regularly monitor the effectiveness of platelet support therapy at clinical level. This can be done using a number of indicators including the proportion of patients who show febrile, allergic and septic reactions, who become and remain refractory to random-donor platelet support, who develop and/or die of hemorrhage not prevented or corrected by platelet support.

AB - Quality assurance of platelet concentrates should include regular determinations on sampled units of platelet concentrate volume, platelet count, pH value and an indicator of maintenance of platelet discoid shape. In regard to the latter, recent investigations suggest that the visual assessment of platelet swirling may provide meaningful and reproducible information with limited staff training and efforts. Other laboratory assays provide useful data that may prove beneficial particulary when new procedures and products are examined. In addition to laboratory tests, it is of utmost importance to regularly monitor the effectiveness of platelet support therapy at clinical level. This can be done using a number of indicators including the proportion of patients who show febrile, allergic and septic reactions, who become and remain refractory to random-donor platelet support, who develop and/or die of hemorrhage not prevented or corrected by platelet support.

KW - Platelet transfusion

KW - Quality assurance

UR - http://www.scopus.com/inward/record.url?scp=21544449470&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=21544449470&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:21544449470

VL - 21

SP - 95

EP - 97

JO - International Journal of Artificial Organs

JF - International Journal of Artificial Organs

SN - 0391-3988

IS - SUPPL. 6

ER -