Quality control of involved-field radiotherapy in patients with advanced Hodgkin's lymphoma (EORTC 20884)

Berthe M P Aleman, Théodore Girinsky, Richard W M Van Der Maazen, Simon Strijk, Paul Meijnders, Roberto Bortolus, Manouk J J Olofsen-Van Acht, Marnix L M Lybeert, Yolande Lievens, Houchingue Eghbali, Evert M. Noordijk, Radka Tomšič, Jacobus H. Meerwaldt, Philip M P Poortmans, Wilma G J M Smit, Antonella Pinna, Michel Henry-Amar, John M M Raemaekers

Research output: Contribution to journalArticle

Abstract

Purpose: To evaluate the impact of the quality of involved-field radiotherapy (IFRT) on clinical outcome in patients with advanced Hodgkin's lymphoma (HL) in complete remission (CR) after six to eight cycles of mechlorethamine, vincristine, procarbazine, prednisone-doxorubicin, bleomycin, and vinblastine (MOPP-ABV) chemotherapy. Methods and Materials: A retrospective review of clinical and radiologic data, radiation charts, simulator films, and megavoltage (MV) photographs was performed. IFRT consisted of 24 Gy to all initially involved nodal areas and 16-24 Gy to all initially involved extranodal sites. Major violations were defined as no or only partial irradiation of an originally involved area, or a total dose

Original languageEnglish
Pages (from-to)1184-1190
Number of pages7
JournalInternational Journal of Radiation Oncology Biology Physics
Volume63
Issue number4
DOIs
Publication statusPublished - Nov 15 2005

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Keywords

  • Advanced Hodgkin's lymphoma
  • Combined modality treatment
  • Quality assurance
  • Quality control
  • Radiotherapy

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Radiation

Cite this

Aleman, B. M. P., Girinsky, T., Van Der Maazen, R. W. M., Strijk, S., Meijnders, P., Bortolus, R., Olofsen-Van Acht, M. J. J., Lybeert, M. L. M., Lievens, Y., Eghbali, H., Noordijk, E. M., Tomšič, R., Meerwaldt, J. H., Poortmans, P. M. P., Smit, W. G. J. M., Pinna, A., Henry-Amar, M., & Raemaekers, J. M. M. (2005). Quality control of involved-field radiotherapy in patients with advanced Hodgkin's lymphoma (EORTC 20884). International Journal of Radiation Oncology Biology Physics, 63(4), 1184-1190. https://doi.org/10.1016/j.ijrobp.2005.03.044