Quality of life and pain control following laparoscopic retroperitoneal lymph node dissection in early-stage nonseminoma

Nicola Nicolai, Elisabetta Bianchi, Ilaria Donati, Camilla L'Acqua, Cinzia Brunelli, Davide Biasoni, Mario Catanzaro, Silvia Stagni, Luigi Piva, Tullio Torelli, Andrea Necchi, Daniele Raggi, Patrizia Giannatempo, Elena Faré, Maurizio Colecchia, Martin Langer, Claudia Borreani, Roberto Salvioni

Research output: Contribution to journalArticlepeer-review

Abstract

Aims and background: To evaluate postoperative pain (PoP) and quality of life (QoL) in patients undergoing open (O-) or laparoscopic (L-) retroperitoneal lymph node dissection (RPLND) for clinical stage I (CS I) and normal markers CS IIA nonseminomatous germ cell tumors. Methods: Since March 2010, a prospective nonrandomized trial evaluated dynamic and rest (R) numeric pain scale (NPS) following patient-controlled analgesia and baseline (T0), 3-month (T3), and 6-month (T6) QoL status assessed by Functional Assessment of Cancer Therapy-General (FACT-G) questionnaire and the Italian-validated Functional Assessment of Chronic Illness Therapy (FACT-T-SG) at T6. Secondary endpoints included length of hospital stay (LHS), interval to recovery (ItR), complications, and oncologic outcomes. Results: In March 2012, 69 (64 CS I) patients were enrolled. Five patients only chose O-RPLND. The PoP and complete QoL data are available in 41 and 56 patients, respectively. The R-NPS significantly improved in days 1-2 vs day 0 (p

Original languageEnglish
Pages (from-to)650-656
Number of pages7
JournalTumori
Volume101
Issue number6
DOIs
Publication statusPublished - Nov 1 2015

Keywords

  • Clinical outcome
  • Germ cell and embryonal
  • Neoplasms
  • Pain management
  • Quality of life
  • Testis neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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