TY - JOUR
T1 - Quality of life and polysensitization in young men with intermittent asthma
AU - Cirillo, Ignazio
AU - Vizzaccaro, Andrea
AU - Klersy, Catherine
AU - Baiardini, Ilaria
AU - Marseglia, Gian Luigi
AU - Canonica, G. Walter
AU - Tosca, Maria Angela
AU - Ciprandi, Giorgio
PY - 2005/6
Y1 - 2005/6
N2 - Background: Health-related quality of life (HRQoL) represents an important variable in asthma management. To date, to our knowledge, no study has explored the relationship between HRQoL and sensitization in patients with asthma. Objective: To evaluate the relationships among HRQoL and sensitization, pulmonary function, and bronchial hyperreactivity in a group of young men with intermittent asthma. Methods: We studied 185 conscripts with intermittent asthma and bronchial hyperreactivity. The Asthma Quality of Life Questionnaire was used. Skin prick testing, spirometry, and methacholine challenge were performed in all participants. Results: The Asthma Quality of Life Questionnaire median scores were greater than 4, indicating suboptimal HRQoL. Polysensitization was significantly associated with the worst HRQoL, whereas pulmonary function and bronchial hyperreactivity category were not. Conclusions: This study provides the first evidence that HRQoL is associated with polysensitization in intermittent asthma and underlines the importance of evaluating this issue when managing young patients with slight respiratory symptoms.
AB - Background: Health-related quality of life (HRQoL) represents an important variable in asthma management. To date, to our knowledge, no study has explored the relationship between HRQoL and sensitization in patients with asthma. Objective: To evaluate the relationships among HRQoL and sensitization, pulmonary function, and bronchial hyperreactivity in a group of young men with intermittent asthma. Methods: We studied 185 conscripts with intermittent asthma and bronchial hyperreactivity. The Asthma Quality of Life Questionnaire was used. Skin prick testing, spirometry, and methacholine challenge were performed in all participants. Results: The Asthma Quality of Life Questionnaire median scores were greater than 4, indicating suboptimal HRQoL. Polysensitization was significantly associated with the worst HRQoL, whereas pulmonary function and bronchial hyperreactivity category were not. Conclusions: This study provides the first evidence that HRQoL is associated with polysensitization in intermittent asthma and underlines the importance of evaluating this issue when managing young patients with slight respiratory symptoms.
UR - http://www.scopus.com/inward/record.url?scp=20544461603&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=20544461603&partnerID=8YFLogxK
M3 - Article
C2 - 15984595
AN - SCOPUS:20544461603
VL - 94
SP - 640
EP - 643
JO - Annals of Allergy, Asthma and Immunology
JF - Annals of Allergy, Asthma and Immunology
SN - 1081-1206
IS - 6
ER -