TY - JOUR
T1 - Quality of life in malignant brain tumor patients following surgery. radiotherapy and chemotherapy
AU - Giovagnoli, A. R.
AU - Pozzi, A.
AU - Silvani, A.
AU - Pelati, O.
AU - Mascheroni, S.
AU - Boiardi, A.
PY - 1997
Y1 - 1997
N2 - Objective to evaluate quality of life (QL) in disease free malignant brain tumor patients Subjects 37 patients submitted to surgery and combined radiotherapy and chemotherapy according to histologie diagnosis, haematologic and physical criteria (Karnofsky Performance Status KPS- > 40) Mean disease duration was 24 months Methods Functional Living Index-Cancer (FLIC), Activities Daily Living (ADL), KPS. State-Trait Anxiety Inventory (STAI), SelfRating Depression Scale (SRDS). Raven Coloured Progressive Matrices (PM), Attentional Matrices (AM), Trail Making Test (TMT), Story Recall (SR) Results. Twenty patients showed FLIC scores (as global indices of QL) higher than 118 and KPS scores equal to or higher than 90 The minimum KPS score of 60 was found in six patients. No patients was demented FLIC scores significantly correlated with KPS, STAI. SRDS, PM, AM and TMT scores (p<01) Female patients showed higher FLIC scores than male patients Regression analisys revealed that the FLIC score was significantly associated with SRDS and AM scores, disease duration, sex, age, education and marital status did not show any relationship A separate regression analysis showed a significant association of the SRDS score with FLIC and TMT scores Conclusions Disease free malignant brain tumor patients may preserve work and fair psychosocial activities. QL appears to be mainly affected by mood slate and mental slowing. Depression may be related to cognitive disabilities and changes of daily life more then to the awareness of coping with a malignant disease.
AB - Objective to evaluate quality of life (QL) in disease free malignant brain tumor patients Subjects 37 patients submitted to surgery and combined radiotherapy and chemotherapy according to histologie diagnosis, haematologic and physical criteria (Karnofsky Performance Status KPS- > 40) Mean disease duration was 24 months Methods Functional Living Index-Cancer (FLIC), Activities Daily Living (ADL), KPS. State-Trait Anxiety Inventory (STAI), SelfRating Depression Scale (SRDS). Raven Coloured Progressive Matrices (PM), Attentional Matrices (AM), Trail Making Test (TMT), Story Recall (SR) Results. Twenty patients showed FLIC scores (as global indices of QL) higher than 118 and KPS scores equal to or higher than 90 The minimum KPS score of 60 was found in six patients. No patients was demented FLIC scores significantly correlated with KPS, STAI. SRDS, PM, AM and TMT scores (p<01) Female patients showed higher FLIC scores than male patients Regression analisys revealed that the FLIC score was significantly associated with SRDS and AM scores, disease duration, sex, age, education and marital status did not show any relationship A separate regression analysis showed a significant association of the SRDS score with FLIC and TMT scores Conclusions Disease free malignant brain tumor patients may preserve work and fair psychosocial activities. QL appears to be mainly affected by mood slate and mental slowing. Depression may be related to cognitive disabilities and changes of daily life more then to the awareness of coping with a malignant disease.
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M3 - Article
AN - SCOPUS:33746352417
VL - 18
SP - 142
JO - Italian Journal of Neurological Sciences
JF - Italian Journal of Neurological Sciences
SN - 0392-0461
IS - 4
ER -