Quality-of-life issues in survivors to anaphylactic reactions to drugs

I. Baiardini, F. Gaeta, G. Molinengo, F. Braido, G. W. Canonica, A. Romano

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this cross-sectional observational study was to explore quality of life and well-being in patients with drug-induced anaphylaxis. Two validated tools were used: the Drug Hypersensitivity Quality-of-Life Questionnaire (DrHy-Q) and the Psychological General Well-Being Index (PGWBI). Sixty-five patients (13 males) underwent data analysis. The mean DrHy-Q score was 62.82 ± 12.1. Mean PGWBI score was 64.03 ± 17.66. DrHy-Q score was significantly correlated with PGWBI total score (r = -0.314; P = 0.011) and with the following domains: Anxiety (r = -0.260; P = 0.036), Depressed mood (r = -0.406; P = 0.001), Positive well-being (r = -0.251; P = 0.004), and General Health (r = -0.352; P = 0.004). Compared with the Italian reference population, patients had a significantly reduced PGWBI total and domain score. Our results highlight for the first time how impaired HRQoL and distress commonly feature in survivors to anaphylactic reactions to drug.

Original languageEnglish
Pages (from-to)877-879
Number of pages3
JournalAllergy: European Journal of Allergy and Clinical Immunology
Volume70
Issue number7
DOIs
Publication statusPublished - Jul 1 2015

Keywords

  • anaphylaxis
  • drugs
  • quality of life
  • well-being

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

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