Quantification of fatty tissue mass by magnetic resonance imaging in arrhythmogenic right ventricular dysplasia

Rossella Fattori, Pierluigi Tricoci, Vincenzo Russo, Luigi Lovato, Letizia Bacchi-Reggiani, Giampaolo Gavelli, Angelo Branzi, Giuseppe Boriani

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Quantification of Fatty Tissue Mass. Introduction: Arrhythmogenic right ventricular dysplasia (ARVD) is a heart muscle disorder in which the pathological substrate is a fatty or fibro-fatty replacement of the right ventricular (RV) myocardium. Methods and Results: Magnetic resonance imaging (MRI) studies were performed in 10 patients with arrhythmogenic right ventricular dysplasia and in 24 matched controls in order to assess right ventricular epicardial/intramyocardial fatty tissue mass, RV myocardial mass, and RV functional parameters. Functional abnormalities were found in all ARVD cases. Patients with ARVD showed increased fatty tissue compared to controls (8.2 ± 4 g vs. 2.0 ± 1.0 g; P = 0.001), whereas no significant differences were found in RV myocardial mass (29.5 ± 9.2 g vs. 23.2 ± 6.7 g; P = NS). A correlation coefficient between 0.87 and 0.97 was found for repeated measurements. Conclusion: Quantification of fatty tissue with MRI is feasible and constitutes an objective method for differentiating normal from pathological conditions. This approach may lead to a complete diagnostic assessment of ARVD with the potential application for monitoring the evolution of the disease.

Original languageEnglish
Pages (from-to)256-261
Number of pages6
JournalJournal of Cardiovascular Electrophysiology
Volume16
Issue number3
DOIs
Publication statusPublished - Mar 2005

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Arrhythmogenic Right Ventricular Dysplasia
Adipose Tissue
Magnetic Resonance Imaging
Myocardium
Muscular Diseases

Keywords

  • ARVD
  • Fatty/adipose tissue
  • MRI

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology

Cite this

Quantification of fatty tissue mass by magnetic resonance imaging in arrhythmogenic right ventricular dysplasia. / Fattori, Rossella; Tricoci, Pierluigi; Russo, Vincenzo; Lovato, Luigi; Bacchi-Reggiani, Letizia; Gavelli, Giampaolo; Branzi, Angelo; Boriani, Giuseppe.

In: Journal of Cardiovascular Electrophysiology, Vol. 16, No. 3, 03.2005, p. 256-261.

Research output: Contribution to journalArticle

Fattori, R, Tricoci, P, Russo, V, Lovato, L, Bacchi-Reggiani, L, Gavelli, G, Branzi, A & Boriani, G 2005, 'Quantification of fatty tissue mass by magnetic resonance imaging in arrhythmogenic right ventricular dysplasia', Journal of Cardiovascular Electrophysiology, vol. 16, no. 3, pp. 256-261. https://doi.org/10.1046/j.1540-8167.2004.40498.x
Fattori, Rossella ; Tricoci, Pierluigi ; Russo, Vincenzo ; Lovato, Luigi ; Bacchi-Reggiani, Letizia ; Gavelli, Giampaolo ; Branzi, Angelo ; Boriani, Giuseppe. / Quantification of fatty tissue mass by magnetic resonance imaging in arrhythmogenic right ventricular dysplasia. In: Journal of Cardiovascular Electrophysiology. 2005 ; Vol. 16, No. 3. pp. 256-261.
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