Quantification of long-term effects of botulinum injection in a case of cerebral palsy affecting the upper limb movement

Erika Molteni, Chiara Rigoldi, Monica Morante, Claudio Rozbaczylo, Mariana Haro, Giorgio Albertini, Manuela Galli, Anna Maria Bianchi

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: The aim of this work was to put into evidence the long-lasting modification induced by botulinum toxin injection and rehabilitative treatment on motor control. Methods: In this contribution, we report the case of a female child showing hemiplegia, due to cerebral palsy. She underwent botulinum injection, followed by physical and occupational therapy. We quantified the biomechanical, cerebral and occupational aspects of her impaired upper limb, also dynamically, with respect to her pre- and post-treatment condition. Results: Small long-lasting improvements-induced on biomechanics by botulinum injection-triggered wide cerebral modification, well reflected in improved contextual movements and motor strategy. Conclusion: These results provide evidences that small modifications in the end-effector performance often imply cerebral modifications and improvement in finalized motor strategy.

Original languageEnglish
Pages (from-to)145-148
Number of pages4
JournalDevelopmental Neurorehabilitation
Volume18
Issue number3
DOIs
Publication statusPublished - Jun 1 2015

Keywords

  • Botulinum injection
  • Cerebral palsy
  • EEG analysis
  • Movement analysis
  • Upper limb

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Rehabilitation
  • Developmental Neuroscience
  • Medicine(all)

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