Quantitation of adriamycin content by a sensitive immunochemical assay

G. Citro, A. Verdina, R. Galati, A. Floridi

Research output: Contribution to journalArticle

Abstract

An immunoenzymatic method for the quantitation of adriamycin (ADM) content in tissues as well as in tumor cells has been developed. This procedure has three main advantages. Firstly, it is possible to carry out the determination on whole homogenates and blood serum, thus avoiding the extractive procedures. Secondly, very low ADM concentrations (0.2 ng) can be detected. Thirdly, it is possible to determine simultaneously and in triplicate both the standard curve and ADM concentration in twelve different samples with a great reduction of the experimental variability.

Original languageEnglish
Pages (from-to)549-552
Number of pages4
JournalAnticancer Research
Volume8
Issue number4
Publication statusPublished - 1988

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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