Quantitative analysis of amineptine (S-1694) in biological samples by gas chromatography-mass fragmentography

C. Sbarra, P. Negrini, R. Fanelli

Research output: Contribution to journalArticle


A sensitive, specific method for the quantitative analysis of amineptine in rat blood and brain is described. After extraction and purification amineptine is detected by mass fragmentography, monitoring the fragment ion at m e 192. The method allows the quantitative analysis of as little as 50 ng of amineptine per ml blood and 200 ng per g for brain.

Original languageEnglish
Pages (from-to)31-38
Number of pages8
JournalJournal of Chromatography B: Biomedical Sciences and Applications
Issue number1
Publication statusPublished - Jan 1 1979


ASJC Scopus subject areas

  • Chemistry(all)
  • Clinical Biochemistry
  • Molecular Medicine

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