Quantitative approach to regional blood flow distribution and wall motion using microsphere myocardial scintigraphy in man

Paolo Marzullo; Claudio Marcassa; Oberdan Parodi; Gianmario Sambuceti; Ezio Maria Ferdeghini; Roberto Testa; Antonio L&apos;Abbate

Quantitative approach to regional blood flow distribution and wall motion using microsphere myocardial scintigraphy in man

Paolo Marzullo, Claudio Marcassa, Oberdan Parodi, Gianmario Sambuceti, Ezio Maria Ferdeghini, Roberto Testa, Antonio L'Abbate

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

A method for quantitative analysis of perfusion and wall motion applied to electrocardiogram-gated images of myocardial 99 mTc albumin microspheres of 99 mTc methoxyisobutil isonitrile, implemented on an Elscint 410M Apex computer system, is described. Quantitative myocardial perfusion was obtained via the ratio between end-diastolic normal reference and patient's angular profiles. A wall thickening index (WTI) was obtained obeying the formula: ((end-systolic profile-end-diastolic profile)/end-diastolic profile) × 100. Compared with regional fractional shortening obtained from biplane contrast ventriculography, microsphere WTI showed sensitivity of 97% and a specificity of 93%. WTI values for methoxyisobutil isonitrile were 82% and 94%, respectively. The proposed count-based method provides simultaneous information on regional perfusion and wall motion.

Original language	English
Title of host publication	Computers in Cardiology
Publisher	Publ by IEEE
Pages	115-118
Number of pages	4
Publication status	Published - 1987

ASJC Scopus subject areas

Software
Cardiology and Cardiovascular Medicine

Cite this

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title = "Quantitative approach to regional blood flow distribution and wall motion using microsphere myocardial scintigraphy in man",

abstract = "A method for quantitative analysis of perfusion and wall motion applied to electrocardiogram-gated images of myocardial 99 mTc albumin microspheres of 99 mTc methoxyisobutil isonitrile, implemented on an Elscint 410M Apex computer system, is described. Quantitative myocardial perfusion was obtained via the ratio between end-diastolic normal reference and patient's angular profiles. A wall thickening index (WTI) was obtained obeying the formula: ((end-systolic profile-end-diastolic profile)/end-diastolic profile) × 100. Compared with regional fractional shortening obtained from biplane contrast ventriculography, microsphere WTI showed sensitivity of 97% and a specificity of 93%. WTI values for methoxyisobutil isonitrile were 82% and 94%, respectively. The proposed count-based method provides simultaneous information on regional perfusion and wall motion.",

author = "Paolo Marzullo and Claudio Marcassa and Oberdan Parodi and Gianmario Sambuceti and Ferdeghini, {Ezio Maria} and Roberto Testa and Antonio L'Abbate",

year = "1987",

language = "English",

pages = "115--118",

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publisher = "Publ by IEEE",

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T1 - Quantitative approach to regional blood flow distribution and wall motion using microsphere myocardial scintigraphy in man

AU - Marzullo, Paolo

AU - Marcassa, Claudio

AU - Parodi, Oberdan

AU - Sambuceti, Gianmario

AU - Ferdeghini, Ezio Maria

AU - Testa, Roberto

AU - L'Abbate, Antonio

PY - 1987

Y1 - 1987

N2 - A method for quantitative analysis of perfusion and wall motion applied to electrocardiogram-gated images of myocardial 99 mTc albumin microspheres of 99 mTc methoxyisobutil isonitrile, implemented on an Elscint 410M Apex computer system, is described. Quantitative myocardial perfusion was obtained via the ratio between end-diastolic normal reference and patient's angular profiles. A wall thickening index (WTI) was obtained obeying the formula: ((end-systolic profile-end-diastolic profile)/end-diastolic profile) × 100. Compared with regional fractional shortening obtained from biplane contrast ventriculography, microsphere WTI showed sensitivity of 97% and a specificity of 93%. WTI values for methoxyisobutil isonitrile were 82% and 94%, respectively. The proposed count-based method provides simultaneous information on regional perfusion and wall motion.

AB - A method for quantitative analysis of perfusion and wall motion applied to electrocardiogram-gated images of myocardial 99 mTc albumin microspheres of 99 mTc methoxyisobutil isonitrile, implemented on an Elscint 410M Apex computer system, is described. Quantitative myocardial perfusion was obtained via the ratio between end-diastolic normal reference and patient's angular profiles. A wall thickening index (WTI) was obtained obeying the formula: ((end-systolic profile-end-diastolic profile)/end-diastolic profile) × 100. Compared with regional fractional shortening obtained from biplane contrast ventriculography, microsphere WTI showed sensitivity of 97% and a specificity of 93%. WTI values for methoxyisobutil isonitrile were 82% and 94%, respectively. The proposed count-based method provides simultaneous information on regional perfusion and wall motion.

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M3 - Conference contribution

AN - SCOPUS:0023458882

SP - 115

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BT - Computers in Cardiology

PB - Publ by IEEE

ER -

Quantitative approach to regional blood flow distribution and wall motion using microsphere myocardial scintigraphy in man

Abstract

ASJC Scopus subject areas

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