TY - GEN
T1 - Quantitative approach to regional blood flow distribution and wall motion using microsphere myocardial scintigraphy in man
AU - Marzullo, Paolo
AU - Marcassa, Claudio
AU - Parodi, Oberdan
AU - Sambuceti, Gianmario
AU - Ferdeghini, Ezio Maria
AU - Testa, Roberto
AU - L'Abbate, Antonio
PY - 1987
Y1 - 1987
N2 - A method for quantitative analysis of perfusion and wall motion applied to electrocardiogram-gated images of myocardial 99 mTc albumin microspheres of 99 mTc methoxyisobutil isonitrile, implemented on an Elscint 410M Apex computer system, is described. Quantitative myocardial perfusion was obtained via the ratio between end-diastolic normal reference and patient's angular profiles. A wall thickening index (WTI) was obtained obeying the formula: ((end-systolic profile-end-diastolic profile)/end-diastolic profile) × 100. Compared with regional fractional shortening obtained from biplane contrast ventriculography, microsphere WTI showed sensitivity of 97% and a specificity of 93%. WTI values for methoxyisobutil isonitrile were 82% and 94%, respectively. The proposed count-based method provides simultaneous information on regional perfusion and wall motion.
AB - A method for quantitative analysis of perfusion and wall motion applied to electrocardiogram-gated images of myocardial 99 mTc albumin microspheres of 99 mTc methoxyisobutil isonitrile, implemented on an Elscint 410M Apex computer system, is described. Quantitative myocardial perfusion was obtained via the ratio between end-diastolic normal reference and patient's angular profiles. A wall thickening index (WTI) was obtained obeying the formula: ((end-systolic profile-end-diastolic profile)/end-diastolic profile) × 100. Compared with regional fractional shortening obtained from biplane contrast ventriculography, microsphere WTI showed sensitivity of 97% and a specificity of 93%. WTI values for methoxyisobutil isonitrile were 82% and 94%, respectively. The proposed count-based method provides simultaneous information on regional perfusion and wall motion.
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M3 - Conference contribution
AN - SCOPUS:0023458882
SP - 115
EP - 118
BT - Computers in Cardiology
PB - Publ by IEEE
ER -