Quantitative assessment of cerebral blood volume by single-photon emission computed tomography

Umberto Sabatini, Pierre Celsis, Gdrard Viallard, Andre Rascol, Jean Pierre Marc-Vergnes

Research output: Contribution to journalArticlepeer-review

Abstract

We implemented a technique for measuring regional cerebral blood volume using single-photon emission computed tomography and in vivo technetium-99m-la be led red blood cells and then evaluated it in nine normal human volunteers (controls) and seven patients with bilateral occlusion or severe stenosis of the internal carotid artery. We also measured regional cerebral blood flow using single-photon emission computed tomography and intravenous xenon-133 in the same subjects. We studied regional cerebral blood flow, regional cerebral blood volume, and their ratio before and after the intravenous injection of 1 g acetazolamide. Mean±SD baseline regional cerebral blood volume was higher in the patients than in the controls (4.1 ±0.6 versus 3.2±0-3 ml/100 g, p

Original languageEnglish
Pages (from-to)324-329
Number of pages6
JournalStroke
Volume22
Issue number3
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Clinical Neurology
  • Advanced and Specialised Nursing
  • Neuroscience(all)

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