Quantitative assessment of changes in left ventricular shape following mitral valve repair

Francesco Maffessanti; G. Tamborini; M. Muratori; M. Zanobini; V. Mor-Avi; L. Sugeng; F. Alamanni; R. M. Lang; M. Pepi; E. G. Caiani

Quantitative assessment of changes in left ventricular shape following mitral valve repair

Francesco Maffessanti, G. Tamborini, M. Muratori, M. Zanobini, V. Mor-Avi, L. Sugeng, F. Alamanni, R. M. Lang, M. Pepi, E. G. Caiani

Centro Cardiologico Monzino

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Mitral valve (MV) repair is the preferential treatment for mitral regurgitation (MR) associated with degenerative MV disease, and the functional benefits of early surgery are known. Our goal was to evaluate the changes in LV shape following MV repair, using a new method based on real-time 3D echocardiography (RT3DE). Fifty patients with severe asymptomatic MR were enrolled. Transthoracic RT3DE imaging was performed the day before, 6 and 12 months after MV repair. A group of 66 normal subjects (NL) was studied as a reference. LV 3D shape indices of sphericity (S) and conicity (C) were computed. Post-operatively, LV volumes were decreased compared to pre-surgical values. EF was slightly decreased 6 months after surgery, but restored at 12 months. Modifications in end-diastolic LV shape were found: prior to surgery, S was elevated and C was decreased compared to NL; at 6 months, these changes were reversed with no further improvement at 12 months. Early MV repair in asymptomatic patients is associated with changes in LV shape which remodels to near normal morphology. Novel 3D shape analysis based on RT3DE, allows serial examination of the complex relationship between LV performance and shape.

Original language	English
Title of host publication	Computers in Cardiology
Pages	33-36
Number of pages	4
Volume	36
Publication status	Published - 2009
Event	36th Annual Conference of Computers in Cardiology, CinC 2009 - Park City, UT, United States Duration: Sep 13 2009 → Sep 16 2009

Other

Other	36th Annual Conference of Computers in Cardiology, CinC 2009
Country	United States
City	Park City, UT
Period	9/13/09 → 9/16/09

ASJC Scopus subject areas

Computer Science Applications
Cardiology and Cardiovascular Medicine

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Quantitative assessment of changes in left ventricular shape following mitral valve repair. / Maffessanti, Francesco; Tamborini, G.; Muratori, M.; Zanobini, M.; Mor-Avi, V.; Sugeng, L.; Alamanni, F.; Lang, R. M.; Pepi, M.; Caiani, E. G.

Computers in Cardiology. Vol. 36 2009. p. 33-36 5445476.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Maffessanti, F, Tamborini, G , Muratori, M , Zanobini, M, Mor-Avi, V, Sugeng, L, Alamanni, F, Lang, RM, Pepi, M & Caiani, EG 2009, Quantitative assessment of changes in left ventricular shape following mitral valve repair. in Computers in Cardiology. vol. 36, 5445476, pp. 33-36, 36th Annual Conference of Computers in Cardiology, CinC 2009, Park City, UT, United States, 9/13/09.

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abstract = "Mitral valve (MV) repair is the preferential treatment for mitral regurgitation (MR) associated with degenerative MV disease, and the functional benefits of early surgery are known. Our goal was to evaluate the changes in LV shape following MV repair, using a new method based on real-time 3D echocardiography (RT3DE). Fifty patients with severe asymptomatic MR were enrolled. Transthoracic RT3DE imaging was performed the day before, 6 and 12 months after MV repair. A group of 66 normal subjects (NL) was studied as a reference. LV 3D shape indices of sphericity (S) and conicity (C) were computed. Post-operatively, LV volumes were decreased compared to pre-surgical values. EF was slightly decreased 6 months after surgery, but restored at 12 months. Modifications in end-diastolic LV shape were found: prior to surgery, S was elevated and C was decreased compared to NL; at 6 months, these changes were reversed with no further improvement at 12 months. Early MV repair in asymptomatic patients is associated with changes in LV shape which remodels to near normal morphology. Novel 3D shape analysis based on RT3DE, allows serial examination of the complex relationship between LV performance and shape.",

author = "Francesco Maffessanti and G. Tamborini and M. Muratori and M. Zanobini and V. Mor-Avi and L. Sugeng and F. Alamanni and Lang, {R. M.} and M. Pepi and Caiani, {E. G.}",

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AU - Maffessanti, Francesco

AU - Tamborini, G.

AU - Muratori, M.

AU - Zanobini, M.

AU - Mor-Avi, V.

AU - Sugeng, L.

AU - Alamanni, F.

AU - Lang, R. M.

AU - Pepi, M.

AU - Caiani, E. G.

PY - 2009

Y1 - 2009

N2 - Mitral valve (MV) repair is the preferential treatment for mitral regurgitation (MR) associated with degenerative MV disease, and the functional benefits of early surgery are known. Our goal was to evaluate the changes in LV shape following MV repair, using a new method based on real-time 3D echocardiography (RT3DE). Fifty patients with severe asymptomatic MR were enrolled. Transthoracic RT3DE imaging was performed the day before, 6 and 12 months after MV repair. A group of 66 normal subjects (NL) was studied as a reference. LV 3D shape indices of sphericity (S) and conicity (C) were computed. Post-operatively, LV volumes were decreased compared to pre-surgical values. EF was slightly decreased 6 months after surgery, but restored at 12 months. Modifications in end-diastolic LV shape were found: prior to surgery, S was elevated and C was decreased compared to NL; at 6 months, these changes were reversed with no further improvement at 12 months. Early MV repair in asymptomatic patients is associated with changes in LV shape which remodels to near normal morphology. Novel 3D shape analysis based on RT3DE, allows serial examination of the complex relationship between LV performance and shape.

AB - Mitral valve (MV) repair is the preferential treatment for mitral regurgitation (MR) associated with degenerative MV disease, and the functional benefits of early surgery are known. Our goal was to evaluate the changes in LV shape following MV repair, using a new method based on real-time 3D echocardiography (RT3DE). Fifty patients with severe asymptomatic MR were enrolled. Transthoracic RT3DE imaging was performed the day before, 6 and 12 months after MV repair. A group of 66 normal subjects (NL) was studied as a reference. LV 3D shape indices of sphericity (S) and conicity (C) were computed. Post-operatively, LV volumes were decreased compared to pre-surgical values. EF was slightly decreased 6 months after surgery, but restored at 12 months. Modifications in end-diastolic LV shape were found: prior to surgery, S was elevated and C was decreased compared to NL; at 6 months, these changes were reversed with no further improvement at 12 months. Early MV repair in asymptomatic patients is associated with changes in LV shape which remodels to near normal morphology. Novel 3D shape analysis based on RT3DE, allows serial examination of the complex relationship between LV performance and shape.

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