Quantitative assessment of Parkinsonian tremor by using biosensor device

Silvia Marino, Emanuele Cartella, Nicola Donato, Nunzio Muscarà, Chiara Sorbera, Vincenzo Cimino, Simona De Salvo, Katia Micchìa, Giuseppe Silvestri, Alessia Bramanti, Giuseppe Di Lorenzo

Research output: Contribution to journalArticlepeer-review


Parkinson disease (PD) is the second most common neurodegenerative disease which affects population older than 65 years. Tremor represents one of the main symptomatic triads in PD, particularly in rest state.We enrolled 41 idiopathic PD patients, to validate the assessment of tremor symptoms.To be enrolled in the study, patients had to fulfill the movement disorder society clinical diagnostic criteria for PD.We used an innovative home-made, low-cost device, able to quantify the frequency and amplitude of rest tremor and stress conditionOur results confirmed the presence of tremor during muscular effort in a significant number of patients and the influence of emotional stress.We suppose that this new device should be validated in clinical practice as a support of differential diagnosis and therapeutic management of PD patients.

Original languageEnglish
Article numbere17897
JournalMedicine (United States)
Issue number51
Publication statusPublished - Dec 1 2019


  • biosensor device
  • Parkinson disease
  • tremor

ASJC Scopus subject areas

  • Medicine(all)


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