TOMOGRAFIA COMPUTERIZZATA QUANTITATIVA (TCQ) DELLA SPONGIOSA VERTEBRALE. PROPOSTA DI UNA METODICA APPLICABILE ALLO STUDIO DELL'OSTEOPOROSI POST-MENOPAUSALE (PMO)

Translated title of the contribution: Quantitative computed tomography (QCT) of vertebral spongiosa. Evaluation of a possible method for management of postmenopausal osteoporosis (PMO)

R. Dore, A. La Fianza, M. Franchi, A. Spinillo, P. Cichero, L. Biazzi

Research output: Contribution to journalArticle

Abstract

A Quantitative Computed Tomography (QCT) method, simplifying the well-known technique proposed by Genant (1982) and applied to a standard third generation whole body CT scanner is described. This technique was applied in the measurement of the trabecular bone which has high sensitivity for metabolic changes. The BMC (Bone Mineral Content) measured in different groups of subjects (healthy postmenopausal patients versus women with postmenopausal osteoporosis) showed a highly significant difference (p <0.001). The precision of repositioning (coefficient of variation 1.8% to 2.3%, obtained in healthy male patients) and the good, linear relationship computed from the phantom values, minimize measurement errors. Since this method is quickly applied and involves low-dose radiation-exposure, it could be introduced in the clinical study of metabolic bone diseases.

Translated title of the contributionQuantitative computed tomography (QCT) of vertebral spongiosa. Evaluation of a possible method for management of postmenopausal osteoporosis (PMO)
Original languageItalian
Pages (from-to)166-170
Number of pages5
JournalRadiologia Medica
Volume74
Issue number3
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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