Quantitative EMG and histological carrier detection of duchenne muscular dystrophy

G. Scarlato, G. Valli, G. Meola, L. Carenini

Research output: Contribution to journalArticlepeer-review

Abstract

Seventy-nine women known as, or suspected to be, carriers of the Duchenne type of muscular dystrophy were examined. The 15 known carriers had an estimation of the CPK serum level and a manual quantitative EMG, which gave the high detection rate of 93%. The 64 suspected carriers had CPK determination and quantitative EMG, or CPK and muscle biopsy, and the value of each technic is discussed. The problem of giving a reassuring answer to women considered to be possible carriers on genetic criteria, but who are not really carriers, is solved if the results of all three tests are negative.

Original languageEnglish
Pages (from-to)235-249
Number of pages15
JournalJournal of Neurology
Volume216
Issue number4
DOIs
Publication statusPublished - Dec 1977

Keywords

  • Carrier, Duchenne
  • EMG quantitative in Duchenne
  • Muscle histology in Duchenne
  • Muscular dystrophy, Duchenne type

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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