Quantitative EMG and histological carrier detection of duchenne muscular dystrophy

G. Scarlato; G. Valli; G. Meola; L. Carenini

doi:10.1007/BF00314048

Quantitative EMG and histological carrier detection of duchenne muscular dystrophy

G. Scarlato, G. Valli, G. Meola, L. Carenini

IRCCS Policlinico San Donato

Research output: Contribution to journal › Article › peer-review

Abstract

Seventy-nine women known as, or suspected to be, carriers of the Duchenne type of muscular dystrophy were examined. The 15 known carriers had an estimation of the CPK serum level and a manual quantitative EMG, which gave the high detection rate of 93%. The 64 suspected carriers had CPK determination and quantitative EMG, or CPK and muscle biopsy, and the value of each technic is discussed. The problem of giving a reassuring answer to women considered to be possible carriers on genetic criteria, but who are not really carriers, is solved if the results of all three tests are negative.

Original language	English
Pages (from-to)	235-249
Number of pages	15
Journal	Journal of Neurology
Volume	216
Issue number	4
DOIs	https://doi.org/10.1007/BF00314048
Publication status	Published - Dec 1977

Keywords

Carrier, Duchenne
EMG quantitative in Duchenne
Muscle histology in Duchenne
Muscular dystrophy, Duchenne type

ASJC Scopus subject areas

Neurology
Clinical Neurology

Access to Document

10.1007/BF00314048

Fingerprint Dive into the research topics of 'Quantitative EMG and histological carrier detection of duchenne muscular dystrophy'. Together they form a unique fingerprint.

Cite this

@article{a919c9e4622a4fcbb2dcf4f432502340,

title = "Quantitative EMG and histological carrier detection of duchenne muscular dystrophy",

abstract = "Seventy-nine women known as, or suspected to be, carriers of the Duchenne type of muscular dystrophy were examined. The 15 known carriers had an estimation of the CPK serum level and a manual quantitative EMG, which gave the high detection rate of 93%. The 64 suspected carriers had CPK determination and quantitative EMG, or CPK and muscle biopsy, and the value of each technic is discussed. The problem of giving a reassuring answer to women considered to be possible carriers on genetic criteria, but who are not really carriers, is solved if the results of all three tests are negative.",

keywords = "Carrier, Duchenne, EMG quantitative in Duchenne, Muscle histology in Duchenne, Muscular dystrophy, Duchenne type",

author = "G. Scarlato and G. Valli and G. Meola and L. Carenini",

year = "1977",

month = dec,

doi = "10.1007/BF00314048",

language = "English",

volume = "216",

pages = "235--249",

journal = "Journal of Neurology",

issn = "0340-5354",

publisher = "Dr. Dietrich Steinkopff Verlag GmbH and Co. KG",

number = "4",

}

TY - JOUR

T1 - Quantitative EMG and histological carrier detection of duchenne muscular dystrophy

AU - Scarlato, G.

AU - Valli, G.

AU - Meola, G.

AU - Carenini, L.

PY - 1977/12

Y1 - 1977/12

N2 - Seventy-nine women known as, or suspected to be, carriers of the Duchenne type of muscular dystrophy were examined. The 15 known carriers had an estimation of the CPK serum level and a manual quantitative EMG, which gave the high detection rate of 93%. The 64 suspected carriers had CPK determination and quantitative EMG, or CPK and muscle biopsy, and the value of each technic is discussed. The problem of giving a reassuring answer to women considered to be possible carriers on genetic criteria, but who are not really carriers, is solved if the results of all three tests are negative.

AB - Seventy-nine women known as, or suspected to be, carriers of the Duchenne type of muscular dystrophy were examined. The 15 known carriers had an estimation of the CPK serum level and a manual quantitative EMG, which gave the high detection rate of 93%. The 64 suspected carriers had CPK determination and quantitative EMG, or CPK and muscle biopsy, and the value of each technic is discussed. The problem of giving a reassuring answer to women considered to be possible carriers on genetic criteria, but who are not really carriers, is solved if the results of all three tests are negative.

KW - Carrier, Duchenne

KW - EMG quantitative in Duchenne

KW - Muscle histology in Duchenne

KW - Muscular dystrophy, Duchenne type

UR - http://www.scopus.com/inward/record.url?scp=0017732477&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017732477&partnerID=8YFLogxK

U2 - 10.1007/BF00314048

DO - 10.1007/BF00314048

M3 - Article

C2 - 72807

AN - SCOPUS:0017732477

VL - 216

SP - 235

EP - 249

JO - Journal of Neurology

JF - Journal of Neurology

SN - 0340-5354

IS - 4

ER -