Quantitative EMG and histological carrier detection of duchenne muscular dystrophy

G. Scarlato; G. Valli; G. Meola; L. Carenini

doi:10.1007/BF00314048

Quantitative EMG and histological carrier detection of duchenne muscular dystrophy

G. Scarlato, G. Valli, G. Meola, L. Carenini

IRCCS Policlinico San Donato

Research output: Contribution to journal › Article › peer-review

Abstract

Seventy-nine women known as, or suspected to be, carriers of the Duchenne type of muscular dystrophy were examined. The 15 known carriers had an estimation of the CPK serum level and a manual quantitative EMG, which gave the high detection rate of 93%. The 64 suspected carriers had CPK determination and quantitative EMG, or CPK and muscle biopsy, and the value of each technic is discussed. The problem of giving a reassuring answer to women considered to be possible carriers on genetic criteria, but who are not really carriers, is solved if the results of all three tests are negative.

Original language	English
Pages (from-to)	235-249
Number of pages	15
Journal	Journal of Neurology
Volume	216
Issue number	4
DOIs	https://doi.org/10.1007/BF00314048
Publication status	Published - Dec 1977

Keywords

Carrier, Duchenne
EMG quantitative in Duchenne
Muscle histology in Duchenne
Muscular dystrophy, Duchenne type

ASJC Scopus subject areas

Neurology
Clinical Neurology

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10.1007/BF00314048

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AU - Valli, G.

AU - Meola, G.

AU - Carenini, L.

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AB - Seventy-nine women known as, or suspected to be, carriers of the Duchenne type of muscular dystrophy were examined. The 15 known carriers had an estimation of the CPK serum level and a manual quantitative EMG, which gave the high detection rate of 93%. The 64 suspected carriers had CPK determination and quantitative EMG, or CPK and muscle biopsy, and the value of each technic is discussed. The problem of giving a reassuring answer to women considered to be possible carriers on genetic criteria, but who are not really carriers, is solved if the results of all three tests are negative.

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KW - Muscle histology in Duchenne

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Quantitative EMG and histological carrier detection of duchenne muscular dystrophy

Abstract

Keywords

ASJC Scopus subject areas

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