Quantitative Sensory Testing (QST) Estimation of Regional Cutaneous Thermal Sensitivity During Waking State, Neutral Hypnosis, and Temperature Specific Suggestions

Gianluca Conversa, Enrico Facco, Matteo Luigi Giuseppe Leoni, Michelangelo Buonocore, Rosa Bagnasco, Lucia Angelini, Laura Demartini, David Spiegel

Research output: Contribution to journalArticle


This study aimed to determine the effects of neutral hypnosis and hypnotic temperature suggestions in thermal and pain thresholds compared to resting state. Sixteen healthy medium or high hypnotizable volunteers were enrolled. Hypnotizability was assessed with the Hypnotic Induction Profile (HIP); QST was checked in resting state, in neutral hypnosis, after suggestions of heat and cold, and after deinduction. A significant increase in heat threshold was recorded during hypnosis with both cold and heat suggestions compared to neutral hypnosis. HIP induction score showed a linear correlation with changes of temperature thresholds after heat and cold suggestions. Thermal suggestions may result in a significant increase of heat perception thresholds with respect to neutral hypnosis. HIP score is related to thermal threshold changes. QST is a valuable and manageable tool to measure temperature threshold change during hypnosis.

Original languageEnglish
Pages (from-to)364-381
Number of pages18
JournalInternational Journal of Clinical and Experimental Hypnosis
Issue number3
Publication statusPublished - Jun 30 2019



  • Adult
  • Cold Temperature
  • Female
  • Hot Temperature
  • Humans
  • Hypnosis
  • Hypnosis, Anesthetic
  • Male
  • Pain Threshold
  • Skin Physiological Phenomena
  • Suggestion
  • Thermosensing/physiology
  • Wakefulness/physiology

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