Quantitative ultrasound at the phalanges in a cohort of monozygotic twins of different ages

Giuseppe Guglielmi, Francesca De Terlizzi, Michelangelo Nasuto, Lorenzo Sinibaldi, Francesco Brancati

Research output: Contribution to journalArticle

Abstract

Results: In children AD-SoS and BTT were positively correlated with age (r = 0.91, r = 0.91), height (r = 0.88, r = 0.90) and weight (r = 0.81, r = 0.87); in adults AD-SoS was negatively related to age (r = −0.36), AD-SoS and BTT were positively related to height (r = 0.37, r = 0.58). Absolute value differences between twins for AD-SoS and BTT were significantly higher in adult twins (25.9 ± 21.9 for AD-SoS and 0.08 ± 0.08 for BTT) than in children (14.5 ± 12.4 for AD-SoS and 0.05 ± 0.04 for BTT).

Conclusion: Differentiation in bone tissue quality in twins increases with age, probably reflecting lifestyle, personal habits, likely acting through epigenetic mechanisms.

Purpose: The aim of our study was to evaluate bone quality by quantitative ultrasound (QUS) at the phalanges in 129 monozygotic twin couples, outlining the differences between growing subjects and adults.

Materials and methods: A total of 129 healthy monozygotic twin couples (42 of children under 18 years of age and 87 of adults) were studied by phalangeal QUS, measuring amplitude-dependent speed of sound (AD-SoS) and bone transmission time (BTT). Anthropometric data were also recorded.

Original languageEnglish
Pages (from-to)277-282
Number of pages6
JournalRadiologia Medica
Volume120
Issue number3
DOIs
Publication statusPublished - 2015

Fingerprint

Monozygotic Twins
Bone and Bones
Epigenomics
Habits
Life Style
Weights and Measures

Keywords

  • Bone mass regulation
  • Bone tissue
  • Hand phalanges
  • Quantitative ultrasound
  • Twins

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Quantitative ultrasound at the phalanges in a cohort of monozygotic twins of different ages. / Guglielmi, Giuseppe; De Terlizzi, Francesca; Nasuto, Michelangelo; Sinibaldi, Lorenzo; Brancati, Francesco.

In: Radiologia Medica, Vol. 120, No. 3, 2015, p. 277-282.

Research output: Contribution to journalArticle

Guglielmi, Giuseppe ; De Terlizzi, Francesca ; Nasuto, Michelangelo ; Sinibaldi, Lorenzo ; Brancati, Francesco. / Quantitative ultrasound at the phalanges in a cohort of monozygotic twins of different ages. In: Radiologia Medica. 2015 ; Vol. 120, No. 3. pp. 277-282.
@article{14363ec0b35d4739a835f889a2e1b919,
title = "Quantitative ultrasound at the phalanges in a cohort of monozygotic twins of different ages",
abstract = "Results: In children AD-SoS and BTT were positively correlated with age (r = 0.91, r = 0.91), height (r = 0.88, r = 0.90) and weight (r = 0.81, r = 0.87); in adults AD-SoS was negatively related to age (r = −0.36), AD-SoS and BTT were positively related to height (r = 0.37, r = 0.58). Absolute value differences between twins for AD-SoS and BTT were significantly higher in adult twins (25.9 ± 21.9 for AD-SoS and 0.08 ± 0.08 for BTT) than in children (14.5 ± 12.4 for AD-SoS and 0.05 ± 0.04 for BTT).Conclusion: Differentiation in bone tissue quality in twins increases with age, probably reflecting lifestyle, personal habits, likely acting through epigenetic mechanisms.Purpose: The aim of our study was to evaluate bone quality by quantitative ultrasound (QUS) at the phalanges in 129 monozygotic twin couples, outlining the differences between growing subjects and adults.Materials and methods: A total of 129 healthy monozygotic twin couples (42 of children under 18 years of age and 87 of adults) were studied by phalangeal QUS, measuring amplitude-dependent speed of sound (AD-SoS) and bone transmission time (BTT). Anthropometric data were also recorded.",
keywords = "Bone mass regulation, Bone tissue, Hand phalanges, Quantitative ultrasound, Twins",
author = "Giuseppe Guglielmi and {De Terlizzi}, Francesca and Michelangelo Nasuto and Lorenzo Sinibaldi and Francesco Brancati",
year = "2015",
doi = "10.1007/s11547-014-0440-x",
language = "English",
volume = "120",
pages = "277--282",
journal = "Radiologia Medica",
issn = "0033-8362",
publisher = "Springer-Verlag Italia s.r.l.",
number = "3",

}

TY - JOUR

T1 - Quantitative ultrasound at the phalanges in a cohort of monozygotic twins of different ages

AU - Guglielmi, Giuseppe

AU - De Terlizzi, Francesca

AU - Nasuto, Michelangelo

AU - Sinibaldi, Lorenzo

AU - Brancati, Francesco

PY - 2015

Y1 - 2015

N2 - Results: In children AD-SoS and BTT were positively correlated with age (r = 0.91, r = 0.91), height (r = 0.88, r = 0.90) and weight (r = 0.81, r = 0.87); in adults AD-SoS was negatively related to age (r = −0.36), AD-SoS and BTT were positively related to height (r = 0.37, r = 0.58). Absolute value differences between twins for AD-SoS and BTT were significantly higher in adult twins (25.9 ± 21.9 for AD-SoS and 0.08 ± 0.08 for BTT) than in children (14.5 ± 12.4 for AD-SoS and 0.05 ± 0.04 for BTT).Conclusion: Differentiation in bone tissue quality in twins increases with age, probably reflecting lifestyle, personal habits, likely acting through epigenetic mechanisms.Purpose: The aim of our study was to evaluate bone quality by quantitative ultrasound (QUS) at the phalanges in 129 monozygotic twin couples, outlining the differences between growing subjects and adults.Materials and methods: A total of 129 healthy monozygotic twin couples (42 of children under 18 years of age and 87 of adults) were studied by phalangeal QUS, measuring amplitude-dependent speed of sound (AD-SoS) and bone transmission time (BTT). Anthropometric data were also recorded.

AB - Results: In children AD-SoS and BTT were positively correlated with age (r = 0.91, r = 0.91), height (r = 0.88, r = 0.90) and weight (r = 0.81, r = 0.87); in adults AD-SoS was negatively related to age (r = −0.36), AD-SoS and BTT were positively related to height (r = 0.37, r = 0.58). Absolute value differences between twins for AD-SoS and BTT were significantly higher in adult twins (25.9 ± 21.9 for AD-SoS and 0.08 ± 0.08 for BTT) than in children (14.5 ± 12.4 for AD-SoS and 0.05 ± 0.04 for BTT).Conclusion: Differentiation in bone tissue quality in twins increases with age, probably reflecting lifestyle, personal habits, likely acting through epigenetic mechanisms.Purpose: The aim of our study was to evaluate bone quality by quantitative ultrasound (QUS) at the phalanges in 129 monozygotic twin couples, outlining the differences between growing subjects and adults.Materials and methods: A total of 129 healthy monozygotic twin couples (42 of children under 18 years of age and 87 of adults) were studied by phalangeal QUS, measuring amplitude-dependent speed of sound (AD-SoS) and bone transmission time (BTT). Anthropometric data were also recorded.

KW - Bone mass regulation

KW - Bone tissue

KW - Hand phalanges

KW - Quantitative ultrasound

KW - Twins

UR - http://www.scopus.com/inward/record.url?scp=84928274952&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84928274952&partnerID=8YFLogxK

U2 - 10.1007/s11547-014-0440-x

DO - 10.1007/s11547-014-0440-x

M3 - Article

C2 - 25091707

AN - SCOPUS:84928274952

VL - 120

SP - 277

EP - 282

JO - Radiologia Medica

JF - Radiologia Medica

SN - 0033-8362

IS - 3

ER -