Quantitative Ultrasound in Osteoporosis and Bone Metabolism Pathologies

Giuseppe Guglielmi, Giacomo Scalzo, Francesca de Terlizzi, W. C G Peh

Research output: Contribution to journalArticlepeer-review


Quantitative ultrasound (QUS) has been introduced in the medical field for the study of bone tissue to identify changes in the tissue that could suggest the presence of osteoporosis and bone fragility. The ultrasound technique is simple, versatile, and its low cost and lack of ionizing radiation have led to the diffusion of this method worldwide. The present article is an overview of the most relevant developments in the field of quantitative ultrasound, in clinical and experimental settings. The advantages and limitations of the present technique and suggestions for its use in the clinical practice are reported.

Original languageEnglish
Pages (from-to)577-588
Number of pages12
JournalRadiologic Clinics of North America
Issue number3
Publication statusPublished - May 2010


  • Amplitude dependent speed of sound
  • Bone quality
  • Broadband ultrasound attenuation
  • Osteoporosis
  • Quantitative ultrasound
  • Quantitative ultrasound index
  • Speed of sound
  • Stiffness

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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