Quantum dots for biomedical applications

Michele Signore, Lance A. Liotta, Ruggero De Maria, Emanuel F. Petricoin

Research output: Contribution to journalArticle

Abstract

Background: Nanotechnology is an emerging field that could have a significant impact on cancer diagnosis, treatment and analysis. Quantum dots represent one of the most interesting nanotechnology-based platforms, and their unique properties make them a potentially versatile tool for molecular diagnostics. Objectives: Here, the most promising uses of quantum dots for translational research are reviewed, ranging from multiplexed immunofluorescence, targeted drug delivery coupled with disease visualization, tumor and sentinel organs localization and long-term cell tracing. Finally, potential future directions for quantum dots as both a diagnostic and therapeutic tool in biomedical research will be explored. Conclusions: The use of quantum dots in biomedical applications is accelerating owing to their unique physical attributes, imaging capabilities, and potential for therapeutic delivery.

Original languageEnglish
Pages (from-to)315-322
Number of pages8
JournalExpert Opinion on Medical Diagnostics
Volume2
Issue number3
DOIs
Publication statusPublished - Mar 2008

Keywords

  • Cancer
  • Imaging
  • Molecular diagnostics
  • Proteomics
  • Quantum dots
  • Reserve-phase array

ASJC Scopus subject areas

  • Molecular Medicine
  • Biomedical Engineering
  • Medicine(all)
  • Biochemistry, medical

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