TY - JOUR
T1 - Quetiapine in acute mania
T2 - A case report (with a six-month follow-up)
AU - Altamura, C.
AU - Madaro, D.
AU - Salvadori, D.
PY - 2001
Y1 - 2001
N2 - Quetiapine is an effective and well-tolerated antipsychotic. To date, experience with quetiapine in bipolar disorders is very limited and information on the use in acute patients is lacking. A patient with a DSM-IV diagnosis of acute mania intolerant to lithium and to neuroleptics was treated with quetiapine. The daily dosage of quetiapine was gradually titrated up to 600 mg t.i.d. Quetiapine was effective, as evidenced by rating scale scores of the BPRS, YMRS and CGI, which dropped by 91% and 94% respectively from baseline (devoid of relevant side-effects). Quetiapine seems to be a promising agent for the treatment of manic episodes in bipolar disorders, although controlled trials are needed.
AB - Quetiapine is an effective and well-tolerated antipsychotic. To date, experience with quetiapine in bipolar disorders is very limited and information on the use in acute patients is lacking. A patient with a DSM-IV diagnosis of acute mania intolerant to lithium and to neuroleptics was treated with quetiapine. The daily dosage of quetiapine was gradually titrated up to 600 mg t.i.d. Quetiapine was effective, as evidenced by rating scale scores of the BPRS, YMRS and CGI, which dropped by 91% and 94% respectively from baseline (devoid of relevant side-effects). Quetiapine seems to be a promising agent for the treatment of manic episodes in bipolar disorders, although controlled trials are needed.
KW - Bipolar disorder
KW - Mania
KW - Quetiapine
UR - http://www.scopus.com/inward/record.url?scp=0035679344&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035679344&partnerID=8YFLogxK
U2 - 10.1080/13651500152732928
DO - 10.1080/13651500152732928
M3 - Article
AN - SCOPUS:0035679344
VL - 5
SP - 283
EP - 285
JO - International Journal of Psychiatry in Clinical Practice
JF - International Journal of Psychiatry in Clinical Practice
SN - 1365-1501
IS - 4
ER -